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Archives of Clinical Infectious Diseases

Infectious Diseases and Tropical Medicine Research Center, SBUMS

e-ISSN 2345-2641
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Cover image of the article: Antimicrobial Resistance Pattern in Urinary Tract Infections in Children on Continuous Ambulatory Peritoneal Dialysis

Image Credit:Arch Clin Infect Dis

Outline

Antimicrobial Resistance Pattern in Urinary Tract Infections in Children on Continuous Ambulatory Peritoneal Dialysis

Authors

Fatemeh Fallah1,*, Hamideh Behzadnia1, Arezou Moradi1, Gita Eslami1, Mostafa Sharifian1, Sedigheh Rafiee Tabatabaei1, Mohammad Ali Malekan1
1Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University, M.C., Tehran, Iran
*Corresponding Author: Pediatric Infectious Research Center, Mofid Children Hospital, Shahid Beheshti University, M.C., Tehran, IR Iran, pedircorg@yahoo.com. Email: pedircorg@yahoo.com
Archives of Clinical Infectious Diseases:Vol. 3, issue 3; 155-9
Published online:Jul 31, 2008
Article type:Brief Report
How to Cite:Fallah F, Behzadnia H, Moradi A, Eslami G, Sharifian M, et al. Antimicrobial Resistance Pattern in Urinary Tract Infections in Children on Continuous Ambulatory Peritoneal Dialysis. Arch Clin Infect Dis. 2008;3(3):. doi:

Abstract

Background:

Growing antibiotic resistance demands the constant reassessment of antimicrobial efficacy, particularly in countries with wide antibiotic abuse. Knowledge of resistance trends is particularly important when prescribing antibiotics empirically, as is usually the case for urinary tract infections (UTIs) especially in children with terminal renal failure on continuous ambulatory peritoneal dialysis (CAPD) treatment. The aim of this study was to analyze the resistance of bacterial isolates to commonly used antibiotics in such patients.

Patients and methods:

In this study, bacterial isolates were evaluated from urine samples collected from pediatric patients (6 months to 17 years) on CAPD with acute UTIs in Tehran from March 2006 through September 2006. Sensitivity was measured by disc diffusion method using NCCLS protocol.

Results:

The most prevalent urinary pathogen was Escherichia coli from 27 cases (75%). In general, the lowest resistance rate of microorganisms was against amikacin (3.7%) and the highest resistance rate was against amoxicillin (70.4%).

Conclusion:

A comparison of these data with those of other countries showed that there was considerable geographic variation in bacterial patterns of sensitivity and resistance properties. Therefore, the selection of antibiotics for empiric therapy especially in children with terminal renal failure on continuous ambulatory peritoneal dialysis (CAPD) treatment should be based on the knowledge of the local conditions.

Highlights

KeywordsUrinary tract infectionContinuous ambulatory peritoneal dialysisAntibiogram

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Copyright

© 2008, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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