Although access to fire has caused extensive changes in daily life and subsequently, development of technology and industrialization, sometimes, insecure use and out of control fire causes accident and destruction, thus the importance of fire safety is clear to everyone (
1). Hospitals and health service providers are a great asset for any country, the destruction and damage of which will have a huge economic burden for a country. When a hospital is destroyed and stops working, large costs are imposed on governments, considering that 70% of ministry of health budgets are spent on hospitals, thus, it is necessary that hospitals are protected from any damage and destruction (
2). In some countries, up to 80% of the health budget are spent on hospitals and health service providers. Rebuilding a destroyed hospital costs double the initial construction cost. Hospitals provide care during 24 hours and cannot be easily evacuated as it is necessary to rescue patients, especially babies and those needing intensive care, thus, hospitals must continue their work and if activity of hospitals and health care providers are disrupted or hospital buildings are damaged, emergency services will be disrupted (
3). This is why the World Health Organization stresses on 2009 messages on protecting hospitals during emergencies (
4). National fire protection association of American, announced during year 2005 that on average over 8000 hospital fires occur around the world each year (
5). From 2006 to 2010, the US fire department responded to around 1400 cases of fire emergencies (
6). On July 26th, 2013, 39 people died in Liaoyuan, Jilin in China due to power failures. On 13 Sept 2013, 37 deaths occurred in Luka, Novgorod in Russia due to fire as a result of cigarette smoking, on April 26th, 2013, in Romanesque near Moscow, 38 people died at a psychiatric hospital due to the electrical short-circuit current and on October 23rd, 2012 at 4:06 in Tainan, Taiwan, 13 people died and 60 people were injured as a result of a fire at a hospital (
7). According to the results of research conducted in the field of fire in developed countries, it is clear that nearly 80% of fires are predictable and preventable and it is clear that by predicting appropriate activities, the 25% remaining damage can be managed appropriately. Studies indicate that about 80% of fires occur in buildings and facilities, in which fire has not occurred previously and this clearly shows that lack of fire incidents for a long period, does not indicate that the place is a safe one (
1). Examples of such events at hospitals, according to the above, shows that observing safety requirements, is important at hospitals and it is essential for each hospital to evaluate its safety conditions. According to international standards, the amount of safety at hospitals will be reduced after 10 years. Overall, 570 hospitals are working in the country, 486 of which are over ten years old or more. The situation of hospitals in the country indicates that the average age of 570 of the country’s public hospitals, are over 35 years old, which are hospitals with poor structures in terms of safety. If only one of these hospitals will be on fire because of the oxygen canisters, medical supplies, alcohol and fuel sources, the fire will intensify. Now, imagine the extant of a fire disaster at a four-storey hospital with 200 beds, with average of at least 170 patients, 30 physicians, 250 nurses, 600 medical and administrative staff, and 140 million dollars of facilities with light and heavy equipment (
8). Johnson et al. performed a risk assessment on the basis of audit methods (
9). In a study by Yarahmadi et al., use of designed methods based on risk assessment was recommended in order to achieve fire safety with appropriate performance (
10). In a study by Mahdinia et al., in 2012, a software-based approach was introduced for risk assessment in order to optimize buildings for fire safety measures and it was concluded that using quantitative risk assessment in the design and implementation of fire protection in buildings is an appropriate method to boost performance (
11). According to the importance and necessity of evaluation and implementation of protective measures to prevent damage, a risk assessment method is required. Unlike building codes that are mostly meant to assure a safe escape or rescue for the occupants, “FRAME” aims at protecting the building, its content, and activities. In one study, the evaluation of fire risk assessment according to FRAME was reported as the most comprehensive, the most transparent, and the most practical method for risk assessment (
12). Some of its advantages are risk quantitative assessment, low cost, applicability in a short time, and evaluation of the present condition before making any attempt for correction. Experience has shown that there is a relationship between risk (R) and the amount of damage. This method can easily be used to evaluate fire risks in existing buildings and in order to avoid long statements on the status of fire safety, it can be stated using a number (
13). The aim of this study was to evaluate alternative methods for fire risk assessment.