Drug abuse is an important concern in Iran, due to its regional location and the kinds of drug that are used (
1). Drug abuse in adolescence and early adulthood are especially problematic during these critical periods of growth as they may impact an individual’s life, including academic achievement. and. Especially as many of these problematic behaviors may continue into adulthood (
2). There is evidence that engaging in risky behaviors reaches its peak during adolescence (
3), and loneliness is one of the factors contributing to drug abuse. Elhageen considered loneliness as a state that leads teenagers to feel inadequate and experience uncomfortable mood states (
4). The term loneliness means isolation, abandonment, and lack of social relationships, which can originate from environmental factors such as moving away, losing loved ones, and being rejected by others; loneliness can also be caused by internal factors, which can occur concurrently with other symptoms of depression (
5,
6). Several studies have indicated that abusing drugs and tobacco (
7), as well as alcohol (
8) correlates with emotional and psychological issues that are related to the perception of loneliness amongst teenagers. Research studies have suggested that isolation and loneliness increase the following: risk of general health problems, such as depression, tendency to attent or commit suicide, levels of stress and mental pressure, cardiovascular disorders and strokes, anti-social behaviors, and drug abuse; studies have also noted decreased learning and retention, weaknesses in decision-making, and impairment in mental functions (
9). Meanwhile, a family’s mental atmosphere affects its members’ lives. This atmosphere is defined as an overall combination of relations among the family members that influence their performance when dealing with issues, barriers, mental stress, anxiety, fear, and other unpleasant stimuli. Home can be defined as family communication patterns associated with relationships among family members, what they say to each other, what they do, and what they perceive from their relationships (
10,
11). The fact that the level of unhealthy and risky behaviors, including drug abuse, is alarmingly high among adolescents and young adults signifies the importance of studying and understanding risky behaviors among these age groups (
12). Studying these behaviors helps us to plan for and invest in the social, psychological and physical health of this population; and to take a major step towards preventing adolescents and young adults from abusing drugs. As stated by Rad et al. studies should help to prevent drug abuse and aid in the construction of educational programs (
13). Since loneliness and family communication may be associated with psychological and behavioral issues, this study aimed to examine the effect of loneliness and family communication on addiction potential among university students. This study sought to answer the following question:
Are loneliness and family communication predictors of addiction potential among university students?