The Association between Serum Resistin Level and Presence or Severity of Coronary Heart Disease

Roozbeh Mortazavi; Akbar Rasekhi Kazerouni; Mohammad Ali Ostovan; Gholamhossein Ranjbar Omrani; Mesbah Shams

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Boards & Committees Indexing and Listing Sources Journal Metrics Publication Ethics and Publication Malpractice Statement Reviewer and AE Registration Form Support Contact Us

APC

Authors Guide Submit Manuscript

The Association between Serum Resistin Level and Presence or Severity of Coronary Heart Disease

Author(s):

Roozbeh Mortazavi¹,

Akbar Rasekhi Kazerouni¹,

Mohammad Ali Ostovan²,

Gholamhossein Ranjbar Omrani³,

Mesbah Shams^3,*

1Department of Internal Medicine, Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

2Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

3Endocrine and Metabolism Research Center, Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran

International Cardiovascular Research Journal:Vol. 11, issue 1; e10563

Published online:Mar 01, 2017

Article type:Research Article

Received:Jul 23, 2016

Accepted:Oct 22, 2016

How to Cite:Mortazavi R, Rasekhi Kazerouni A, Ostovan MA, Ranjbar Omrani G, Shams M. The Association between Serum Resistin Level and Presence or Severity of Coronary Heart Disease. Int Cardiovasc Res J. 2017;11(1):e10563. doi:

Abstract

Background: Obesity is a well-known principal risk factor for metabolic disorders and cardiovascular diseases. Resistin is one of adipocyte-derived molecules, which plays important roles in inflammation as well as in endocrine and cardiovascular systems.
Objectives: The present study aimed to determine the association between serum resistin level and presence/severity of Coronary Heart Disease (CHD).
Patients and Methods: This cross-sectional study was conducted on 155 individuals referred for coronary angiography. Information about the patients’ age, gender, and cardiovascular risk factors was recorded. Their weight, height, and waist and hip circumferences were measured, as well. Each coronary angiogram was reported for two scoring methods (number of vessel diseases (usual method) and Gensini scoring system) by one cardiologist who was not aware of the participants’ serum resistin levels. Then, the relationship between serum resistin level and presence/severity of CHD was evaluated.
Results: The results revealed no significant associations between the mean serum resistin level and the presence of CHD by both methods of evaluation of the coronary angiograms after adjustment for all conventional risk factors for CHD. In addition, no significant association was detected between serum resistin level and the severity of CHD based on the usual method of reporting the coronary angiograms (number of vessel diseases) (P = 0.332). Yet, serum resistin level was positively correlated to body mass index and waist and hip circumferences and negatively related to height and fasting blood sugar level. Moreover, no linear correlation was found between serum resistin level and Gensini score (P = 0.35). Finally, hip circumference (P = 0.002) and height (P = 0.018) were determined as the predictors of serum resistin level.
Conclusions: This cross-sectional study showed no significant associations between serum resistin level and presence/severity of CHD.

Keywords

Fulltext

The full text is available in PDF.

References

1.
The references are available in PDF.

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 3 weeks ago
Scopus by Title: 0
Last Update: 3 weeks ago
Scopus by Title (Ref): 0
Last Update: 3 weeks ago
CrossRef: 0
Last Update: 6 days ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

Roozbeh Mortazavi:[PubMed][Scholar]
Akbar Rasekhi Kazerouni:[PubMed][Scholar]
Mohammad Ali Ostovan:[PubMed][Scholar]
Gholamhossein Ranjbar Omrani:[PubMed][Scholar]
Mesbah Shams:[PubMed][Scholar]

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

Outlines

The Association between Serum Resistin Level and Presence or Severity of Coronary Heart Disease

Abstract

Fulltext

References

Last Update: 3 weeks ago

Last Update: 3 weeks ago

Last Update: 3 weeks ago

Last Update: 6 days ago