For years, human society has been challenged with drug addiction and sustained notable financial and spiritual losses. The problem of drug addiction is one of the top four world crises and the main social crisis in Iran. Drug addiction has to do with economic and cultural aspects and the like (
1). Given the cultural factors, wrong beliefs, and unique geographical position, Iranian youth are at a high risk of drug addiction (
2). Unfortunately, about 60% of Iranian prisons are filled by drug addicts and those convicted for drug related crimes. This means that notable resources of the country in different fields are wasted to deal with the crisis. Drug addiction is the root of insecurities in the society and poses threats to health and hygiene of the patient and the society as the whole (
3). Among the destructive effects of drug addiction are aggressiveness, cognitive nervous breakdown, dissatisfaction with marital life (both the addict and the spouse), family life disorders, loss of interest in sexual relationships, anxiety, depression, and problems in public health (
4-
11). Due to medical, health, economic, social, and legal problems caused by drug abuse, the society needs to seriously pay more attention to effective preventive strategies (
12,
13). Choosing the right strategy to deal with mental pressures can be effective in decreasing the effect of these pressures on physical and psychological heath of the patients (
14,
15). One of the strategies proposed by the researchers is life skills training. The term “life skills” refers to a large set of mental, social, and interpersonal skills that can help people make more informed decisions, effectively interact with others, enjoy physical-mental and social health, and deal with challenges and needs of their daily lives (
3). In general, life skills training is a comprehensive and general program that actually deals with the skills that an individual needs for life. Skills like self-awareness, proper communication, decision making, problem solving, anger management, and handling stress are of the main concepts dealt in training (
16). Participation in life skills workshops provides an opportunity for drug addicts to meet and communicate with others who have the same problem. The participants can share their remedies and approaches to deal with drug abuse, avoid recurrence, and handle temptations. They can provide multilateral support to improve the chance of keeping away from the drug. Moreover, intra-network social supports are against the sense of seclusion and isolation and foster interpersonal relationships (
17). Malouff, Thorsteinsson, and Schutte (2007) carried out a meta-analysis study to examine the effect of interventions based on life skills trainings on attenuating mental and physical problems of 2895 participants in Australia and showed that the majorities of studies in this area had emphasized the effectiveness of the intervention (
18). The trainings have been helpful for controlling smoking and drinking habits and drug abuse (
19-
22), preventing violence and crime (
16), preventing suicide (
19), improving emotional and social adaptation, decreasing anxiety, and preventing sexual promiscuity (
23,
24). Life skills training program is designed to improve the mental health and prevent social damages. The bedrock of the program is the academic research on mental and social damages and its main purpose is to create opportunities to learn professional skills along with life skills (
16,
25,
26). According to authors, there are two types of coping styles known as “problem-centered coping” and “emotion-centered coping.” Choosing these styles depends on one’s assessment of the situation (primary assessment) and his/her capability to deal with the situation (secondary assessment). Researchers have gained a great insight by examining coping styles of successful and unsuccessful individuals. They have found that people who manage problems successfully usually have equipped themselves with a variety of coping skills, and life skills training adds to one’s coping skills (
15,
16,
25,
27). World Health Organization (WHO) has listed these skills along with introducing actual practices. The key to have these skills is to practice and use them in daily life. The listed skills are self-awareness skills, empathy, effective communication, interpersonal skill, stress coping skill, managing emotions, problem solving skill, decision making skill, creative thoughts, and critical thinking skill (
16,
19). Nurses play an effective role at three prevention levels. Public education about a healthy lifestyle constitutes the main part of the first level of prevention (
28-
30).
Stability of drug abuse prevention programs in Iran is very limited because they mostly follow a one-dimension approach (e.g. reducing availability of the drugs) and novel approaches are mostly implemented for a short period of time and merely on the basis of public informing measures, which are far away from being considered as large scale health improvement interventions (
31). Fortunately, drug abuse preventive programs have recently been steered toward adopting a wider social perspective. In this regard, the life skill educational program to prevent drug abuse is a novel preventive approach in which the main focus is on development of personal and social skills (
32). Literature review revealed that there were few studies on the effects of life skills education on social relationships of the health service seekers referring to drug clinics. Therefore, the present study is an attempt to introduce a safe and affordable educational program and help the health service seekers develop their social relationships. Three sources of parents, spouse, and friends are focused by the program.