Fulltext
The full text of this article is available on the PDF file.
Zahedan Journal of Research in Medical Sciences
The Official Journal of Zahedan University of Medical Sciences
e-ISSN 2383-2894
Image Credit:Zahedan J Res Med Sci
Outline
Effects of Echinacea Purpurea onWound Healing after Arsenic Induced Skin Necrosis
Authors
Annahita Rezaie1,*, Hossein Najafzadeh2, Mahdi Poormahdi-Broojeni3, Babak Mohammadian1, Marzieh Heidari4
1Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran
2Department of Basic Sciences, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran
3Department of Food Hygiene, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran
4Graduated in Veterinary Medicine, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran
*Corresponding Author: Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran Email: rezaie20a@yahoo.com
Published online:Jan 26, 2013
Article type:Research Article
Received:Jan 19, 2012
Accepted:Jul 03, 2012
How to Cite:Rezaie A, Najafzadeh H, Poormahdi-Broojeni M, Mohammadian B, Heidari M. Effects of Echinacea Purpurea onWound Healing after Arsenic Induced Skin Necrosis. Zahedan J Res Med Sci. 2013;15(11):e92787. doi:
Abstract
Background: Evaluation of healing effects of Echinacea extract in Arsenic induced dermal necrosis in rat is the objective of this study.
Materials and Methods: In this experimental study 20 male Wistar rats were divided to 2 groups. Dermal necrosis was induced by subcutaneously arsenic injection (4mg/kg) for 10 days. In group 2, after arsenic receiving, Echinacea were injected intraperitoneally (400mg/kg). After last day of injection, rats were euthanizes and pathologic samples were collected from dermal ulcers.
Results: Histopathologic results revealed necrosis of different dermal layers in arsenic group. There were inflammatory exudates instead of impaired structures. In group 2, there were granulation tissue with high cellularity and new vessels.
Conclusion: According to this research findings arsenic can induce dermal necrosis which is a good animal model for dermatologic researches and also Echinacea has healing effects and can protect and limit the Arsenic effects.
Highlights
References
- 1.The References of this article are available on the PDF file.
Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
4
May
2013
Effects of Echinacea purpurea on Hepatic and Renal Toxicity Induced by Diethylnitrosamine in Rats
Annahita Rezaie,
Ali Fazlara,
Mojtaba Haghi Karamolah,
Ali Shahriari,
Hossein Najaf Zadeh,
Marzieh Pashmforosh
Rezaie A, Fazlara A, Haghi Karamolah M, Shahriari A, Najaf Zadeh H, et al. Effects of Echinacea purpurea on Hepatic and Renal Toxicity Induced by Diethylnitrosamine in Rats. Jundishapur J Nat Pharm Prod. 2013;8(2):60-64. doi: https://doi.org/10.17795/jjnpp-9686
31
May
2026
Clinical Evaluation of Chitagel in Chronic Wound Healing: A Complementary Bioactive Gel with Echinacea Extract and Quaternary Ammonium-Modified Chitosan
Shohreh Fahimirad,
Hasan Jafari,
Morteza Sanagooiezadeh Isfahani,
Mohammadreza Memarzadeh,
Amir Almasi Hashiani,
Hamid Abtahi
Fahimirad S, Jafari H, Sanagooiezadeh Isfahani M, Memarzadeh M, Almasi Hashiani A, et al. Clinical Evaluation of Chitagel in Chronic Wound Healing: A Complementary Bioactive Gel with Echinacea Extract and Quaternary Ammonium-Modified Chitosan. Jundishapur J Nat Pharm Prod. 2026;21(2):e170761. doi: https://doi.org/10.5812/jjnpp-170761
5
Nov
2016
The Topical Effect of Cappariss spinosa Extract on Burn Wound Healing
Mojtaba Kalantar,
Mehdi Goudarzi,
Hossein Foruozandeh,
Amir Siahpoosh,
Mohammad Javad Khodayar,
Sara Mahmoodi Koshkghazi
Kalantar M, Goudarzi M, Foruozandeh H, Siahpoosh A, Khodayar MJ, et al. The Topical Effect of Cappariss spinosa Extract on Burn Wound Healing. Jundishapur J Nat Pharm Prod. 2018;13(1):e35690. doi: https://doi.org/10.5812/jjnpp.35690
22
Jan
2020
Wound Healing and the Effect of ANNAS; a New Product of AnbarNesa
Khojasteh Joharchi,
Seyyed Mahdi Anaraki Firouz,
Fatemeh Mashhadiabbas,
Ardalan Mansouri,
Hasanali Shafiee,
Jamileh Bigom Taheri
Joharchi K, Anaraki Firouz SM, Mashhadiabbas F, Mansouri A, Shafiee H, et al. Wound Healing and the Effect of ANNAS; a New Product of AnbarNesa. Jundishapur J Nat Pharm Prod. 2020;15(2):e66668. doi: https://doi.org/10.5812/jjnpp.66668
5
Mar
2023
The effect of a topical ointment containing methanol extract of Buxus hyrcana Pojark. leaves on cutaneous wound healing in rats
Fereshteh Amiri,
fatemeh mirzaee,
Paria Fadaee Heydarabadi,
Reza Enayatifard,
Hamid Reza Goli,
Somayeh Shahani
Amiri F, mirzaee F, Fadaee Heydarabadi P, Enayatifard R, Goli HR, et al. The effect of a topical ointment containing methanol extract of Buxus hyrcana Pojark. leaves on cutaneous wound healing in rats. koomesh. 2023;25(1):e152801. doi:
Cited by
- Scopus by DOI: 0
Last Update: 1 week ago
- Scopus by Title: 0
Last Update: 1 week ago
- Scopus by Title (Ref): 0
Last Update: 1 week ago
- CrossRef: 0
Last Update: 3 hours ago
- OpenAlex: 0
Last Update: 6 hours ago
- OpenCitations: 0
Last Update: 5 days ago
Comments
Number of Comments:0