Effects of oral vitamin C supplement on the serum lipid profile

Mojgan  Mohajeri-Iravani; Ebrahim Hazrati; Shahram Firuz-Marani Firuz-Marani

Annals of Military and Health Sciences Research

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Editors and Boards Indexing and Listing Sources Reviewer and AE Registration Form Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support

Authors Guide Submit Manuscript

Effects of oral vitamin C supplement on the serum lipid profile

Author(s):

Mojgan Mohajeri-Iravani ¹,

Ebrahim Hazrati^2,*,

Shahram Firuz-Marani Firuz-Marani³

1Department of Anesthesiology and Critical Care, Andorra

2, AJA University of Medical Sciences, Iran

3Tehran, Iran, Andorra

Annals of Military and Health Sciences Research:Vol. 13, issue 1; e62671

Published online:Feb 25, 2015

Article type:Research Article

Received:Dec 16, 2014

Accepted:Jan 21, 2015

How to Cite:Mojgan Mohajeri-Iravani Ebrahim HazratiShahram Firuz-Marani Firuz-MaraniEffects of oral vitamin C supplement on the serum lipid profile.Ann Mil Health Sci Res.13(1):e62671.

Abstract

Purpose: Ascorbic acid has protective effects against coronary heart disease. These effects are attributed to its antioxidant properties and its relation to plasma lipids. This study investigated the effects of supplementing one gram of vitamin C per day on the serum serum lipoproteins of healthy 18 to 55 years old individuals in Iran.

Materials and Methods: This study was conducted on 55 healthy individuals aged 18 to 55 years old at a medical center of Iran’s Army. None of the participants had taken vitamin supplements three months before participating in the study. Their diet patterns were evaluated by estimating the energy and nutrients intake. At the beginning of the study, serum triglyceride, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and total cholesterol levels of the participants were measured. Then, the participants received one gram of vitamin C on a daily basis for 30 days. Blood parameters were measured on the 15th and 30th days of supplementation and were compared with each other. The findings were analyzed with Student’s t-test and analysis of variance (ANOVA) test using Statistical Package for Social Sciences (SPSS) software version 18.

Results: After receiving vitamin C supplement for 30 days, a significant reduction was seen in the participants’ total cholesterol level (12.2%) and average plasma triglyceride concentration level (8.09%). HDL cholesterol level significantly increased (14.5%) after one month of vitamin C supplementation (P =.032).

Conclusion: Taking one gram of vitamin C daily may significantly reduce serum lipoprotein levels in healthy individuals.

Keywords

vitamin C

lipid profile

lipoprotein

cardiovascular diseases

antioxidant properties

Fulltext

full text is available in PDF.

References

1.
References is available in PDF.

comments