Quantum Dots and their application in bioimaging

Background: fluorescent semiconductor nanocrystals also known as quantum dots or qdots are tiny light-emitting nanocrystals (2-10 nm) that have captivated researchers in many field from electronic, materials science to biological applications over the past two decades. This article is attempted to review current approaches to the property, synthesis, solubilization, and functionalization of qdots and their applications to cell and animal biology. The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics Materials and Methods: As particular properties of quantum dots that gives those suitable nominate for using instead of traditional materials in biological imaging. In following, the latest achieved researches on these type of materials are described and the works that are doing on them for increase solubility in water, biocompatibility, and hybridization with biological compound and also introducing them in biological system are expressed. Conclusions: In this review article, in the first physical and chemical property of quantum dots has been investigated. Some advantage and difficulty due to these properties in utilizing has been discussed and beneficial procedure for improvement and modifying them has been explained and in the last some quantum dots application in biological imaging has been stated.