Obesity as an Important Risk Factor for Certain Types of Cancer

Sayed Hossain Davoodi; Talieh  Malek-Shahabi; Ali Malekshahi-Moghadam; Roghieh Shahbazi; Saeideh Esmaeili

International Journal of Cancer Management

The Official Journal of Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences

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Obesity as an Important Risk Factor for Certain Types of Cancer

Author(s):

Sayed Hossain Davoodi¹,

Talieh Malek-Shahabi²,

Ali Malekshahi-Moghadam³,

Roghieh Shahbazi¹,

Saeideh Esmaeili^4,*

1Dept. of Clinical Nutrition and Dietetics, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences, Food Science and Technology, Shahid Beheshti University of Medical Sciences,Tehran, Iran

2Dept. of Molecular genetics, Shahid Beheshti University, Tehran, Iran

3Faculty of Veterinary Medicine, Tehran University , Tehran, Iran

4Dept. of Food Technology Research, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

International Journal of Cancer Management:Vol. 6, issue 4; e80466

Published online:Dec 30, 2013

Article type:Review Article

Received:Aug 19, 2013

Accepted:Sep 28, 2013

How to Cite:Sayed Hossain DavoodiTalieh Malek-ShahabiAli Malekshahi-MoghadamRoghieh ShahbaziSaeideh EsmaeiliObesity as an Important Risk Factor for Certain Types of Cancer.Int J Cancer Manag.2013;6(4):e80466.

Abstract

Cancer could be described as the uncontrolled and unrestricted growth of malignant cells in any place of the body. It is a multifactorial disease which either heredity or environmental factors (such as nutrition, physical inactivity, alcohol, obesity, exposure to sun, environmental pollutants, infections) chip in incidence of cancer. In recent years, several researchers have focused on obesity as a potent cancer risk factor. Scientificevidences have suggested that obesity has associated with increased risk for a plenty of different types of cancer. The evidences are the most consistent for endometrial cancer, breast cancer between the postmenopausal women, and renal cell cancer. More contradictoryresults have reported about the colorectal, prostate, and pancreatic cancer. Although numerous studies have done according to the obesity and cancer relation or joint, but the molecular mechanisms in which obesity could increase the risks of cancer, have been poorly understood.

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