Gastrointestinal Stromal Tumors: Epidemiology and Treatment Outcomes

Hassan Peyvandi; E Haji Nasrollah; SA Mousavian; P Daryaii; R Yeganeh; A Davati; GR Ghanei

International Journal of Cancer Management

The Official Journal of Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences

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Gastrointestinal Stromal Tumors: Epidemiology and Treatment Outcomes

Author(s):

Hassan Peyvandi^1,*,

E Haji Nasrollah²,

SA Mousavian³,

P Daryaii⁴,

R Yeganeh²,

A Davati⁵,

GR Ghanei⁶

1Assistant professor of general surgery, Shahid Beheshti University (MC), Loghman Medical Center, Iran

2Associate professor of general surgery, Shahid Beheshti University (MC), Loghman Medical Center, Iran

3Resident of general surgery, Shahid Beheshti University (MC), Loghman Medical Center, Iran

4Assistant professor of general surgery, Tehran University of Medical Sciences, Cancer Institute, Iran

5Assistant professor of public medicine- Shahed Medical School, Iran

6Resident of general surgery, Tehran University of Medical Sciences, Sina Medical Center, Iran

International Journal of Cancer Management:Vol. 2, issue 3; e80566

Published online:Sep 30, 2009

Article type:Research Article

Received:Sep 30, 2009

Accepted:Sep 30, 2009

How to Cite:Hassan PeyvandiE Haji NasrollahSA MousavianP DaryaiiR YeganehA DavatiGR Ghaneiet al.Gastrointestinal Stromal Tumors: Epidemiology and Treatment Outcomes.Int J Cancer Manag.2(3):e80566.

Abstract

Introduction: Numerous studies have investigated the prevalence, incidence and clinical manifestations of gastrointestinal stromal tumors (GISTs). However, little is known about GISTs in Iran. This pioneer study focuses on description of 36 patients with GISTs in Iran.

Methods: A database was created for 36 patients suffering from GIST who were treated in Loghman Medical Center and Tehran Cancer Institute in Tehran, Iran. Information on age, sex, clinical manifestations, treatment and outcomes were recorded and analyzed using SPSS version 13.

Results: Patients had an average age of 60 years; and 16 of them were males. The disease was most commonly manifested by abdominal mass, weight loss, and anemia. Twenty one patients had a mass smaller than 10cm; and in 33 patients KIT test was positive. In the follow-up, 5 patients experienced relapse and 3 succumbed due to advanced cancer.

Conclusion: Primary results showed that GISTs might have different manifestations and incidence in Iran compared to other parts of the world. We hope that this study could serve as a starting point for the better understanding and classification of this disease in Iran and for development of improved management strategies.

Keywords

gastrointestinal stromal tumors (gist)

surgery

Iran

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