Colorectal Cancer Nutritional Risk Factors: A Population Based Case-Control Study

A Keshtkar; SH Semnani; Sima Besharat; M Aboomardani; N Abdolahi; GH Roshandel; A Moradi; S Besharat; KH Kalavi; HS Mirkarimi; SZ Hashemi Nasab; M Teimoorian; M Tavasoli

International Journal of Cancer Management

The Official Journal of Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences

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Colorectal Cancer Nutritional Risk Factors: A Population Based Case-Control Study

Author(s):

A Keshtkar¹,

SH Semnani²,

Sima Besharat^1,*,

M Aboomardani¹,

N Abdolahi¹,

GH Roshandel¹,

A Moradi¹,

S Besharat¹,

KH Kalavi¹,

HS Mirkarimi¹,

SZ Hashemi Nasab¹,

M Teimoorian¹,

M Tavasoli¹

1Golestan Research Center of Gastroenterology and Hepatology (GRCGH),Golestan University of Mediacal SciencesGolestan, Iran

2Golestan Research Center of Gastroenterology and Hepatology (GRCGH),Golestan University of Mediacal SciencesGolestan; 2. Department of Gastroenterology, Golestan University of Mediacal Sciences,Golestan,Iran, Iran

International Journal of Cancer Management:Vol. 3, issue 2; e80677

Published online:Jun 30, 2010

Article type:Research Article

Received:Dec 20, 2009

Accepted:Apr 28, 2009

How to Cite:A KeshtkarSH SemnaniSima BesharatM AboomardaniN AbdolahiGH RoshandelA MoradiS BesharatKH KalaviHS MirkarimiSZ Hashemi NasabM TeimoorianM Tavasoliet al.Colorectal Cancer Nutritional Risk Factors: A Population Based Case-Control Study.Int J Cancer Manag.3(2):e80677.

Abstract

Background: Colorectal cancer (CRC) is the third common malignancy all over theworld. Modern life styles affecting nutritional habits have been providing apotential impact on CRC. This study aims to assess the nutritional characteristics in CRC patients of Golestan province, Northeast of Iran.

Methods: All incident CRC cases (N47) in northeast of Iran (2004-2005) and a matched number of healthy persons were selected as cases and controls respectively. The subects filled the Questionnaires containing socio-demographic and nutritional characteristics (FFQ).

Results: Data analysis showed that Total Energy Expenditure (TEE) higher than1 837.5 Kcal/ day (first quartile of TEE) was significantly related to CRC risk (0R 3.8; 95% Cl:1.2 - 11.3); no other relationship was reported.

Conclusions: Findings suggested that higher levels of total energy expenditure may increase the risk of CRC about 4-fold. We also found that there are relationships between CRC and high fat diets or cooking methods. Nutritional interventions should be considered as an important part in colorectal cancer prevention programs.

Keywords

Colorectal cancer

Nutrition and risk factor

Iran

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