Iranian communities have experienced substantial changes in recent years. Shifts in sexual and social criteria, as well as communication technologies, have caused substantial changes and disrupted traditional values. Free time and pleasure-seeking have been transformed, increasing the risk of unhealthy and dangerous behaviors, leading to increases in well-known diseases. In the last two years, the crisis of addiction and suicide among the students, as underlined by the Central Department of Consultancy for students in the Ministry of Science and Technology, has proposed some preventive plans and research programs. Addiction to narcotic drugs is regarded as the most predominant and complex problems in the human community. The addict population is estimated to be about two million people. However, it seems clear that the real number is much larger than that reported (
1). In a study entitled “Personality disorders and committing suicide,” Hosainian and his colleagues (
2) stated that personality disorders such as avoidance, antisocial, schizoid, borderline, paranoid, and passive-aggressive personality disorders are among factors that increase the chance of committing suicide among Iranian. It is worth noting that integration of these factors with alcohol and drug abuse further increases the likelihood of committing suicide (
2). Another study investigating the prevalence rates of different categories of youth risk behavior by age, sex, and parental education using 26,111 Hong Kong students found that less than one-third of the participants consumed an unhealthy diet frequently, 18% had tried smoking, and 14.5% had seriously considered attempting suicide (
3). Solaimani (
4), in his article “Risky behavior and prevention from AIDS in adolescents,” stated that the risk behaviors increasing the chance of being infected with HIV in adolescence include the following: 1) Having many sexual partners and unsafe intercourse, 2) Drugs and narcotics abuse by injection, 3) Abnormal sexual relations, 4) Abuse of alcohol and hallucinatory drugs, 5) Tattooing, 6) Lack of information and awareness in accordance with age 7) Family problems and leaving home, 8) Poverty and financial problems, 9) Being ejected with contaminated blood or blood products, 10) High-risk or dangerous jobs, 11) Being infected with other diseases through sexual relations, and 12) exposure to HIV from the mother at the time of delivery (
4). Panahandeh (
5) in a study investigating levels of student awareness about HIV and Hepatitis B in Iranshahr universities revealed that 9% had good awareness, 74% had an average awareness, and 17.3% had a poor awareness (
5). According to the researcher, health care training and providing essential information play a critical role in establishing this knowledge. Taghipoor (
6) in her research examining the level of student awareness in Islamic Azad University-Zahedan asserts that 86% were aware of the epidemiology of HIV, 60% know the signs of the disease, and 14% were aware of methods of prevention. She concluded that general student knowledge about the epidemiology and pathology of this disease was at a desirable level (
6). In another study, Musavi (
7) examined the probability of an explosive increase in HIV in Iran by comparing sociological indices of two different groups of countries. The first group included countries that experienced an explosion in the cases of HIV (A countries) and those that experienced a slower growth of HIV (B countries). Musavi (
7) states that B countries were considered different from A countries in along the following dimensions: 1) Being non-Muslim 2) Serving as a destination for immigration 3) Being a destination for the tourism industry 4) Experiencing ethnic conflicts 5) Experiencing intense economic crises 6) Undergoing complex social crises 7) Having issues in health care. The researcher believes that an explosion of the numbers of AIDS cases by at least 1400 is unlikely (
7). Generally, due to the profound changes in social circumstances in recent years, adolescents typically engage in the risk and harmful behaviors (
8). In a study entitled “Violence among high school students in Thailand,” Sherer and Sherer (
9) explored the prevalence and severity of violent behavior among high school students in relation to family, peers, schools, and neighborhoods. According to this study, males were more violent than females. The strongest predictor of violence was violence in the youth’s environment followed by peer influences and personal characteristics (
9). Toprak, Sadik et al. (
10) examined factors associated with illicit drug abuse among Turkish college students, demonstrating that the major risk factors were contact with a person, such as a family member or a peer, who practiced substance abuse, poor school performance, being arrested or in trouble with the police, and burglary or theft (
10). Toprak, Sadik et al. (
10) examined self-harm, suicidal thoughts, and suicide attempts among college students. Their finding showed that tranquilizer abuse played a dual role as a correlate for suicide ideation and as a means of attempting suicide. Additionally, they found that drug abusers and adolescents who practiced self-harm presented the highest suicide risk (
11). Serras et al. (
12), in their study examining self-injurious behavior (SIB), substance use, and associated risk factors in a multi-campus probability sample of college students, found that drug use and frequent binge drinking were associated with higher rates of SIB. Among those who engaged in any SIB, those who used drugs had higher depression rates, higher prevalence of cigarette smoking, and higher rates of binge eating. In a multiple logistic regression model predicting SIB, depression, cigarette smoking, gambling, and drug abuse were significant predictors. Information about those at risk of SIB is critical in the design of prevention and intervention efforts as colleges continue to grapple with risk behaviors (
12). With respect to the established studies, the present research aims to investigate the profile of drug abuse in students of all universities are under inspection by the Ministry of Science. Given the broader aim of determining student drug abuse patterns, the specific goals of the research include examining the correlations among the kinds of drugs, gender, and region of residence. This study also seeks to examine the rate of legal involvement of students regarding drug abuse, comparing the patterns derived from different informational resources and comparing students on drug abuse patterns based on demographic variables.