A Novel Method for Quantification of Left Ventricular Noncompaction Using Two-Dimensional Echocardiography in Children

Keyhan  Sayadpour Zanjani; Ahmad  Ghamei Khosroshahi; Armen  Kocharian; Aliakbar  Zeinaloo; Abdolrazagh Kiani; Elaheh  Malakan Rad

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

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A Novel Method for Quantification of Left Ventricular Noncompaction Using Two-Dimensional Echocardiography in Children

Author(s):

Keyhan Sayadpour Zanjani^1,*,

Ahmad Ghamei Khosroshahi²,

Armen Kocharian³,

Aliakbar Zeinaloo⁴,

Abdolrazagh Kiani⁵,

Elaheh Malakan Rad⁶

IJ Pediatrics:Vol. 23, issue 5; 519-524

Published online:Jun 10, 2013

Article type:Research Article

Received:Sep 28, 2012

Accepted:May 08, 2013

How to Cite:Keyhan Sayadpour ZanjaniAhmad Ghamei KhosroshahiArmen KocharianAliakbar ZeinalooAbdolrazagh KianiElaheh Malakan Radet al.A Novel Method for Quantification of Left Ventricular Noncompaction Using Two-Dimensional Echocardiography in Children.Iran J Pediatr.23(5):519-524.

Abstract

Objective: Although there are several echocardiographic criteria, there is not yet a general consensus about the diagnosis of left ventricular noncompaction. The current criteria are mostly based on the areas with maximal noncompaction in the heart. The echocardiographer may miss this maximal point leading to a misdiagnosis. Accordingly, we suggested a new method to measure the percentage of myocardial noncompaction using two-dimensional echocardiography. Methods: In this study, the new method was examined on 4 noncompaction and 26 dilated cardiomyopathies, and 25 normal subjects. The percentage of noncompaction was measured at 3 levels (apical, papillary muscle and mitral valve) and averaged. Findings: The mean percentages of myocardial noncompaction were 3.59±2.27, 8.86±5.52 and 34.7±26.1 in the control, dilated cardiomyopathy and noncompaction groups, respectively. A value of 17% or greater could distinguish left ventricular noncompaction from dilated cardiomyopathy with 92% specificity and 100% sensitivity and from normal subjects with 100% specificity and sensitivity. This percentage had a statistically significant association with noncompacted to compacted myocardial thickness ratio (P

Keywords

Left Ventricular Noncompaction

Cardiomyopathy

Echocardiography

Children

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