Innovative Journal of Pediatrics
The Scientific Journal of Growth & Development Research Center
e-ISSN 3117-5341
Outline
Is There any Association Between Passive Smoking and Esophagitis in Pediatrics?
Authors
Maryam Monajemzadeh1,*, Mohammad-Taghi Haghi-Ashtiani2, Roohallah Soleymani3, Sedigheh Shams4, Shayandokht Taleb5, Farzaneh Motamed6, Mehri Najafi7, Ata Abbasi8
Published online:Feb 13, 2013
Article type:Research Article
Received:Sep 02, 2012
Accepted:Nov 11, 2012
How to Cite:Monajemzadeh M, Haghi-Ashtiani M, Soleymani R, Shams S, Taleb S, et al. Is There any Association Between Passive Smoking and Esophagitis in Pediatrics?. Inn J Pediatr. 2013;23(2):. doi:
Abstract
Objective: Exposure to environmental tobacco smoke (ETS) is one of the major factors of predisposing children to develop several hazardous health problems. We decided to investigate the association between nicotinine, one of the nicotine metabolites and esophagitis in children with gastroesophageal reflux disease (GERD).
Methods: In a case control study 46 children suffering from esophagitis referred to endoscopy ward were recruited. The control group consisted of 45 healthy children. Urine samples were collected and urinary cotinine level (UCL) measured.
Findings: The mean age of esophagitis and control groups were 5.11±2.93 and 6.72±2.8 respectively. Sixty children were passive smokers; 31 of them had non-smoker parents. In control group, 32 (71.1%) children and in esophagitis group 29 (63%) children had non-smoker parents. The mean value of UCL in patients suffering from esophagitis was significantly higher than those in normal group (P=0.04, 24.98±6.4 ng/ml vs. 15.16 ± 3.9 ng/ml). Considering 50ng/ml as a cutoff point for UCL, it was significantly higher in passive smoker group than in non smoker group (P=0.02). The mean cotinine level differed significantly in esophagitis and control group.
Conclusion: Our results indicate the increased risk of developing esophagitis in children with ETS exposure.
Highlights
References
- 1.References are available on the PDF.
Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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