Short-Term Outcomes of Very Low Birth Weight Infants Born at a Tertiary Care Hospital, Istanbul, Turkey

Deniz Atalay; &Ouml;zg&uuml;l Salihoğlu; Emrah Can; Ayşeg&uuml;l Beşkardeş; Sami Hatipoğlu

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

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Short-Term Outcomes of Very Low Birth Weight Infants Born at a Tertiary Care Hospital, Istanbul, Turkey

Author(s):

Deniz Atalay¹,

Özgül Salihoğlu^2,*,

Emrah Can³,

Ayşegül Beşkardeş⁴,

Sami Hatipoğlu⁵

IJ Pediatrics:Vol. 23, issue 2; 205-211

Published online:Jan 24, 2012

Article type:Research Article

Received:Dec 28, 2011

Accepted:Nov 25, 2012

How to Cite:Deniz AtalayÖzgül SalihoğluEmrah CanAyşegül BeşkardeşSami HatipoğluShort-Term Outcomes of Very Low Birth Weight Infants Born at a Tertiary Care Hospital, Istanbul, Turkey.Iran J Pediatr.23(2):205-211.

Abstract

Objective: To evaluate mortality and short-term outcomes in very low birth weight infants admitted to the tertiary neonatal intensive care unit, Istanbul, Turkey.
Methods: Study data were recorded prospectively from January 1, 2010, to December 31, 2010. The clinical findings in neonates with birth weights <1000g were compared with infants with birth weights of between 1000g and 1499g.
Findings: In the present study, survival rates were 40% and 86.2% for infants weighing <1000g and 1000g to 1499g, respectively. There was no difference between males and females with respect to mortality (P>0.05). The mean (±standard deviation) birth weight was 985.6±150.15 g and mean gestational age was 27.5±2.04 weeks. The antenatal steroid rate was 37.2%, and the Cesarean section rate was 73%. Respiratory distress syndrome was diagnosed in 89% of the infants, with a 69% surfactant administration rate. Severe intracranial hemorrhage (IVH) (grade >II) was 14%. Grade 4 periventricular leukomalacia was 10%. Twelve (24%) infants had evidence of bronchopulmonary dysplasia (BPD). Retinopathy of prematurity (stage >II) was 4%. The correlation between ROP rate and need for ventilation therapy was present (r=0.52). Proven necrotizing enterocolitis (stage >2) was not observed. Patent ductus arteriosus (PDA) was diagnosed in 67% of the neonates. BPD, IVH, and PDA were statistically higher in neonates with a birth weight <1000g.
Conclusion: Survival rate of VLBW infants increased with increasing BW. Sex was not a risk factor for mortality. The need for ventilatory therapy may be an important risk factor for ROP in infants <1500g.

Keywords

Mortality

Morbidity

Neonate

Very Low Birth Weight

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