Innovative Journal of Pediatrics
The Scientific Journal of Growth & Development Research Center
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Generalized Lymphadenopathy in Infancy; a Case Report
Author(s):
Published online:Dec 15, 2012
Article type:Case Report
Received:Aug 24, 2011
Accepted:Jul 17, 2012
How to Cite:Mamishi S, Movahedi Z, Mohammadzadeh V, Sabouni F. Generalized Lymphadenopathy in Infancy; a Case Report. Inn J Pediatr. 2013;23(1):. doi:
Abstract
Background: Rosai-Dorfman disease (RDD) is a rare disease of histiocytic cells, a cause of benign cervical lymphadenopathy (LAP) and massive generalized lymph node enlargement in children and adults. There are also some reports on involvement of other human body organs with or without LAP.
Case Presentation: A 7-month-old infant with chief complaint of generalized massive LAP was referred to our center. RDD was diagnosed according to clinical manifestations and confirmed through histopathologic and immunoreactivity study on the obtained sample by cervical lymph node biopsy.
Conclusion: RDD is not a malignant illness and lymph node enlargement most often decreases in its size happens without special treatment.
References
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Copyright
© 2013, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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