Third-Degree Heart Block in Thalassemia major: A Case Report

Ali R. Maleki; Bagher Nikyar; Seyed M. Hosseini

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

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Third-Degree Heart Block in Thalassemia major: A Case Report

Author(s):

Ali R. Maleki^1,*,

Bagher Nikyar ²,

Seyed M. Hosseini ³

1Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran

2Department of Pediatrics, Golestan University of Medical Sciences, Gorgan, Iran

3Department of Physiology, Golestan University of Medical Sciences, Gorgan, Iran

IJ Pediatrics:Vol. 22, issue 2; 260-264

Published online:Jun 30, 2012

Article type:Case Report

Received:Dec 13, 2010

Accepted:Oct 07, 2011

How to Cite:Ali R. MalekiBagher Nikyar Seyed M. Hosseini Third-Degree Heart Block in Thalassemia major: A Case Report.Iran J Pediatr.22(2):260-264.

Abstract

Background: First and second-degree heart blocks are partly common rhythm disorders in thalassemic patients but complete heart block is a very rare complication of iron overload cardiomyopathy.
Case Presentation: This 15-year-old boy, a known case of major β-thalassemia was admitted to our emergency unit with dyspnea and cough because of decompensated heart failure. The electrocardiogram showed complete heart block with junctional escape rhythm. Interestingly, his previous electrocardiogram taken 2 months earlier, had some PVC and second degree, Mobitz type 1 (Wenckebach) heart block. After improvement of dyspnea and control of blood pressure in normal range, the patient was referred to ER. A dual-chamber permanent pacemaker was implanted and his symptoms improved, but he died 24 days after discharge from hospital.
Conclusion: We present a rare case of complete heart block after a second-degree (Mobitz 1) heart block that was due to severe iron overload cardiomyopathy.

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