Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings

authors:

avatar Hamid Nasri 1 , avatar Mahmoud Rafieian-Kopaei 2 , *

. Email:rafieian@yahoo.com

how to cite: Nasri H , Rafieian-Kopaei M. Metformin and Diabetic Kidney Disease: A Mini-Review on Recent Findings. Iran J Pediatr. 2014;24(5): 565-568. 

Abstract

Metformin, an oral anti-diabetic agent in the biguanide class is a widely prescribed drug to treat high blood glucose in patients with type 2 diabetes mellitus. Metformin has three different roles, including blood glucose regulatory effect, protection of kidney tubular cell by acting as an effective antioxidant and finally ameliorative effect on diabetic kidney disease through saving the podocytes. Therefore, diabetic patients may benefit from all of these three distinct ameliorative effects.

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