Morbidity and Mortality in Iranian Children with Juvenile Systemic Lupus erythematosus

Fariba  Tavangar-Rad; Vahid Ziaee; Mohammad-Hassan  Moradinejad; Fatemeh  Tahghighi

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

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Morbidity and Mortality in Iranian Children with Juvenile Systemic Lupus erythematosus

Author(s):

Fariba Tavangar-Rad¹,

Vahid Ziaee^2,*,

Mohammad-Hassan Moradinejad³,

Fatemeh Tahghighi⁴

IJ Pediatrics:Vol. 24, issue 4; 365-370

Published online:Jul 01, 2014

Article type:Research Article

Received:Dec 24, 2013

Accepted:Apr 14, 2014

How to Cite:Fariba Tavangar-RadVahid ZiaeeMohammad-Hassan MoradinejadFatemeh TahghighiMorbidity and Mortality in Iranian Children with Juvenile Systemic Lupus erythematosus.Iran J Pediatr.24(4):365-370.

Abstract

Objective: Juvenile systemic lupus erythematosus (JSLE) is a common rheumatologic disorder that involves multi organ systems. Prognosis of lupus in children may be poorer than in adults. In this study, we determined mortality and morbidity rates in the pediatric SLE in Iran.Methods: In a cross sectional study, we evaluated 120 children with SLE who had registered in our pediatric rheumatology database within 2004-2010. Data including sex, age, remission, age at the time of diagnosis, age at the time of study, various types of organ involvement, mortality and remission were extracted from this database.Findings: From 120 cases, 77% (92 cases) were females and 23% (28 cases) males (F:M=3.3). Mean follow up period was 56±32 months and mean age at the time of manifesting disease 10.34±2.9 years. Mortality rate was 10% (12 cases) in our investigation. Musculoskeletal involvement showed significant difference between various age groups (P

Keywords

Systemic Lupus Erythematosus

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