The Association between Weight for Gestational Age and Kidney Volume: A Study in Newborns in India

Kirtisudha  Mishra; Vikram Datta; Aarushi  Aarushi; Maninder Kaur Narula; R. Subramanyam Iyer; Sushma Nangia

Innovative Journal of Pediatrics

The Scientific Journal of Growth & Development Research Center

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The Association between Weight for Gestational Age and Kidney Volume: A Study in Newborns in India

Author(s):

Kirtisudha Mishra^1,*,

Vikram Datta²,

Aarushi Aarushi³,

Maninder Kaur Narula⁴,

R. Subramanyam Iyer⁵,

Sushma Nangia⁶

Innovative Journal of Pediatrics:Vol. 24, issue 1; 93-99

Published online:Jan 29, 2013

Article type:Research Article

Received:Sep 06, 2013

Accepted:Nov 03, 2013

How to Cite:Mishra K, Datta V, Aarushi A, Kaur Narula M, Iyer R S, et al. The Association between Weight for Gestational Age and Kidney Volume: A Study in Newborns in India.Inn J Pediatr.2013;24(1):93-99.

Abstract

Objective: The association of low birth weight (LBW) with adult onset diseases like hypertension is suggested to be partially mediated by a low number of nephrons at birth. Studies have established a relation between LBW and renal volume as the latter is a surrogate marker of total nephron number. Most such studies have considered birth weight or gestational age as separate independent predictors, without taking into consideration the baby’s weight with respect to its gestational age. This study aims to investigate the influence of weight for gestational age on kidney volume in newborns. Methods: Consecutive newborns delivered in the department of neonatology in a tertiary care medical college and hospital, were included in a cross-sectional study. The subjects were classified as appropriate for gestational age (AGA) and small for gestational age (SGA) as per Lubchenco’s charts of weight for gestational age (WGA). Bilateral kidney dimensions were measured by a single observer and combined kidney volumes were calculated and compared between the groups. Findings: Four hundred and seventeen newborns (SGA 159; AGA 258) were included. The mean combined kidney volume (CKV) was significantly lower among SGA newborns (13.85±4.02 cm3) compared to that of AGA (16.88±4.53 cm3) (P

Keywords

Small for Gestational Age

Newborn

Kidney

Low Birth Weight

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