Cover image of the article: Does Cigarette Smoking Have a Protective Effect Against Parkinson's Disease?

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Does Cigarette Smoking Have a Protective Effect Against Parkinson's Disease?

Authors

Seyed Ali Masoud1,*
1Associate professor of Neurology, Kashan University of Medical Sciences, Kashan, Iran
*Corresponding Author: Associate professor of Neurology, Kashan University of Medical Sciences, Kashan, Iran, Tel: +98-3615550026-9, Fax: +98-3615558900 Email: masoud_s_a@yahoo.com

IJ Psychiatry and Behavioral Sciences:Vol. 2, issue 2; 46-9
Published online:Jul 31, 2008
Article type:Research Article
Received:Jun 09, 2008
Accepted:Jul 09, 2008
How to Cite:Masoud SA. Does Cigarette Smoking Have a Protective Effect Against Parkinson's Disease?. Iran J Psychiatry Behav Sci. 2008;2(2):. doi:

Abstract

Objective: Previous studies reported that individuals with Parkinson’s disease are less likely to have smoking history and it seems that nicotine has a neuroprotective effect. The authors have conducted a casecontrol retrospective study to determine if there is an association between cigarette smoking and Parkinson’s disease.

Methods: In a matched case-control study, 92 individuals with Parkinson’s disease (71 men, 21 women; mean age: 67.3±11 year) were compared to 184 people without such a diagnosis. (144 men, 40 women; mean age: 65.7±12.3 year).

Results: Nineteen patients in the group with a diagnosis of Parkinson’s disease (20.6%) were smoker. In the control group, however, there were 103 smokers. Also, we found a dose-response correlation between amount of smoking and higher risk of having Parkinson’s diseas.

Conclusion: Consistent with the results of previous studies, we found that individuals with Parkinson’s disease are significantly less likely to have smoked regularly than those without Parkinson’s disease.

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Copyright

© 2008, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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