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IJ Psychiatry and Behavioral Sciences
IJPBS is the Official Journal of Mazandaran University of Medical Sciences
e-ISSN 1735-9287
p-ISSN 1735-8639
Outline
The Pattern of Adherence in Patients with Bipolar I Disorder; an Eight Weeks Study
Authors
1Tehran Psychiatric Institute, Mental Health Research Centre, Iran University of Medical Sciences and Health Services, Tehran, Iran
2Tehran Psychiatric Institute, Mansouri St, Niyayesh St, Sattarkhan Ave, Tehran, Iran
*Corresponding Author: Tehran Psychiatric Institute, Mansouri St, Niyayesh St, Sattarkhan Ave, Tehran, Iran, Tel: +98-2166551655 Email: [email protected]
Published online:Dec 31, 2009
Article type:Research Article
Received:Jul 05, 2009
Accepted:Sep 29, 2009
How to Cite:Sharifi A, Shabani A, Ahmadzad-Asl M. The Pattern of Adherence in Patients with Bipolar I Disorder; an Eight Weeks Study. Iran J Psychiatry Behav Sci. 2009;3(2):. doi:
Abstract
Objectives: Non-adherence limits the effectiveness of medications among patients with bipolar disorder. Many studies have investigated the predicting factors of non-adherence. This paper aims to present the pattern of adherence in patients with bipolar I disorder (BID).
Methods: Seventy six patients with BID enrolled in a prospective study. The Medication Possession Ratio (MPR) was used to evaluate patients' adherence to medications, and repeated measure analysis was performed to reveal the pattern of variations. A Persian translation of Drug Attitude Inventory (DAI-10) (shortened version) was used to assess the attitude of patients toward medications.
Results: the repeated measure analysis revealed that the adherence to medications successively decreased (p<0.001). Age, gender, marital status, educational level, comorbid substance abuse did not alter the pattern.
Conclusion: There is a decreasing pattern in the adherence to medications among BID patients, regardless of known predicting factors of non-adherence. It means even fully adherent patients could potentially become non-adherents during the course of maintenance treatment.
References
- 1.References are available in the PDF.
Copyright
© 2009, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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