Validity of Persian Version of Mood Disorder Questionnaire in Diagnosis of Bipolar Mood Disorder in Depressive Phase

Mohammad Ali Ghoreishizadeh; Shahrokh Amiri; Mohammad Zakaria Pezeshki; Farhad Bakhtshadi; Fatemeh Ranjba

IJ Psychiatry and Behavioral Sciences

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Validity of Persian Version of Mood Disorder Questionnaire in Diagnosis of Bipolar Mood Disorder in Depressive Phase

Author(s):

Mohammad Ali Ghoreishizadeh¹,

Shahrokh Amiri^2,*,

Mohammad Zakaria Pezeshki¹,

Farhad Bakhtshadi¹,

Fatemeh Ranjba¹

1Department of Psychiatry, Tabriz University of Medical Sciences, Tabriz, Iran

2Assistant professor of Child and Adolescent Psychiatry, Department of Psychiatry, Tabriz University of Medical Sciences, Tabriz, Iran

IJ Psychiatry and Behavioral Sciences:Vol. 5, issue 1; 50-5

Published online:Jun 30, 2011

Article type:Research Article

Received:Apr 10, 2010

Accepted:Jan 12, 2011

How to Cite:Mohammad Ali GhoreishizadehShahrokh AmiriMohammad Zakaria PezeshkiFarhad BakhtshadiFatemeh RanjbaValidity of Persian Version of Mood Disorder Questionnaire in Diagnosis of Bipolar Mood Disorder in Depressive Phase.Iran J Psychiatry Behav Sci.5(1):50-5.

Abstract

Objective: The Mood disorder questionnaire (MDQ) has been designed as a screening self-report inventory for diagnosing bipolar mood disorders. This study investigated the validity and the optimal cut-off threshold of the Persian version of MDQ in a group of Iranian depressive patients.

Methods: One hundred and twenty patients with probable diagnosis of mood disorders attending psychiatric clinics were recruited to this cross-sectional study. The structured clinical interview for DSM-ΙV (SCID) was employed as the gold standard of diagnosis to discriminate between unipolar and bipolar depressions. Translated version of MDQ in Persian was completed by the patients and the final scores were summed up by a physician. The sensitivity and specificity of MDQ were calculated and compared with the diagnosis made by SCID. The ROC curve was used to determine the optimal cut-off point for diagnostic accuracy.

Results: Ninety patients with bipolar depression and 30 patients with unipolar depressive disorder completed the MDQ. Internal reliability of MDQ was good with a Cronbach's alpha coefficient of 0.773. Regarding the original scoring criteria (symptoms and supplementary questions), the sensitivity and specificity of MDQ for bipolar disorder were 70% and 100% respectively. In current study, the optimal cut-off score without applying the supplementary questions was calculated to be 6 or more, with a sensitivity of 80% and a specificity of 93.3%.

Conclusion: MDQ appears to be a useful screening tool for bipolar depression in Iranian psychiatric practice.

Conflict of Interest: This paper is not related to financial profits of the authors and was supported by Tabriz University of Medical Sciences.

Declaration of Interest: None.

Citation: Ghoreishizadeh MA, Amiri SH, Pezeshki MZ, Bakhtshadi F, Ranjbar F. Validity of Persian Version of Mood Disorder Questionnaire in Diagnosis of Bipolar Mood Disorder in Depressive Phase. Iranian Journal of Psychiatry and Behavioral Sciences 2011; 5(1): 50-5.

Keywords

Bipolar Disorder

Mood Disorder Questionnaire

Sensitivity

Specificity

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