The Efficacy of Intermittent Walking in Water on the Rate of MHPG sulfate and the severity of depression

authors:

avatar Valiollah Dabidy Roshan 1 , * , avatar Mehdi Pourasghar 2 , avatar Zeinab Mohammadian 3

Associate Professor of Physical Education and Sport Sciences, Department of sport Physiology, University of Mazandaran, Babolsar, Iran
Psychiatry and Behavioral Sciences Research Center , Mazandaran University of Medical Sciences, Sari, Iran
College of Physical Education and Sport Sciences, Department of sport Physiology, University of Mazandaran, Babolsar, Iran
Iranian Journal of Psychiatry and Behavioral Sciences: Vol.5, issue 2; 26-31
published online: September 02, 2011
article type: Original Article
received: November 06, 2010
revised: July 08, 2011
accepted: April 10, 2011

How To Cite Dabidy Roshan V, Pourasghar M, Mohammadian Z. The Efficacy of Intermittent Walking in Water on the Rate of MHPG sulfate and the severity of depression. Iran J Psychiatry Behav Sci. 2011;5(2): 26-31. 

Abstract

Objective: Many studies evaluated the efficacy of exercise on some depression indices, but the effect of physical exercise in exhilarating milieu on urine 3-Methoxy-4-Hydroxyphenylglycol (MHPG) sulfate-the main metabolite of norepinephrine is not clear. The purpose of this research was to study the effect of a six-week intermittent walking in the water on 24-hour urine MHPG sulfate in depressed female teenagers.
Methods: Twenty-four high school female students with depression were divided randomly into case and control group. Pool walking exercise program was implemented 3 sessions weekly for 6 weeks and with a rate of 60-70% of the maximum heart rate. The control group didnít enter any exercise protocol and did not receive any other anti-depressant therapy. HPLC-fluorometric detection assay was used to measure 24-hour urine MHPG sulfate values. The data was analyzed with t-test and Piersonís correlation tests.
Results: Twenty hour urine MHPG sulfate increased from 1.93 (±0.59) to 4.66 (±0.85) micromole in case group (P ≤ 0.001), and in control group from 1.67 (±0.58) to 1.80 (±0.58) micromole. Increase of 24-hour urine MHPG sulfate and increasing of maximum oxygen consumption showed significant positive correlation (r = 0.65), and a significant negative correlation (r = 0.65) was observed between urine MHPG sulfate and Hamilton Rating Scale for Depression (Ham-D) score.
Conclusion: Aerobics training in exhilarating environments shows desirable influence over reduction of depression. This reduction of depression is correlated with MHPG sulfate elevation.
Declaration of Interest: None.
Clinical Trial Registration: URL: #_> http://www.Irct.ir/Unique identifier: IRCT201104251457N8
Citation: Dabidy Roshan V, Pourasghar M, Mohammadian Z. The efficacy of intermittent walking in water on the rate of MHPG sulfate and the severity of depression.. Iran J Psychiatry Behav Sci 2011; 5(2): 26-31.

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