Abstract
Background:
Epilepsy is a severe problem incorporating a high degree of the misconception that influences the quality of life of individuals suffering from the disease.Objectives:
The purpose of the present study was to assess the knowledge and attitudes of patients with epilepsy toward the disease.Methods:
A cross-sectional study was conducted on 155 individuals with epilepsy aged ≥ 18 years from August 2016 to Jun 2018 in an outpatient clinic of a medical university in Sari City, North of Iran. Thirty-four closed-ended questions were developed, including 14 items about knowledge, 11 items about attitudes, and nine questions about knowledge profile-personal toward epilepsy. Answers to the questions were either “yes,” “no,” or “I do not know.” The chi-square (χ2) test was used to explain the association between variables and demographic information.Results:
The mean age of the participants was 31.73 ± 11.06 years. Regarding the cause of epilepsy, 85.8% of the participants reported that epilepsy is a brain disorder. Moreover, in terms of the knowledge score, 54.8% of the participants had a fair knowledge of epilepsy. Accordingly, patients with university education had good knowledge about the disease (P = 0.007). In terms of attitudes toward epilepsy, 82.6% of the patients had a positive attitude toward the disease but had no good awareness of it. These positive attitudes were associated with a high education level (P = 0.001).Conclusions:
This study showed that despite the positive attitude toward epilepsy, good knowledge about the disease was still below 50%.Keywords
1. Background
Epilepsy is the most common chronic illness of the brain that affects people of all ages, genders, and races. It is estimated that more than 70 million people globally have epilepsy, and 80% of them live in developing countries (1, 2). The point prevalence of active epilepsy has been estimated at 6.38 per 1,000 persons (3). A systematic review and meta-analysis conducted in Iran showed the prevalence of epilepsy to be around 5% (4). Epilepsy brings about severe problems with an extraordinary amount of social stigma, having a destructive effect on the quality of life (QOL) of people with epilepsy (PWE), especially in developing countries (5-8). These patients experience several social, psychological, and economic problems associated with poor QOL (9, 10).
The lack of knowledge about epilepsy is associated with negative attitudes and beliefs, as well as a prominent stigma at the workplace and school (1-11). Many people with epilepsy endure intense degrees of depression, anxiety, and fatigue, and are susceptible to social and occupational restrictions that usually are conveyed with the disease diagnosis (12, 13). Several factors can affect the QOL of these patients. These factors include social determinants, family situations, seizure occurrence, and proportion of response to treatment (14, 15). In a previous study carried out in Iran, unemployment and low education were expressively associated with a high level of stigma development (16). Good knowledge about epilepsy is connected with a lower extent of stigmatization and social separation, as well as a lower level of depression and misconception (17). Beside improved self-effectiveness and social care, a positive attitude toward the disease is effective in ameliorating self-handling (18, 19). Hence, it is relevant to determine the attitudes and knowledge of patients with epilepsy. Although several studies have been performed in Iran on the knowledge and attitudes about epilepsy, they have mostly focused on specific community groups such as relatives, teachers, general populations, and other groups (15, 20-22).
2. Objectives
The attitudes and knowledge of PWE toward their disease have been inadequately investigated. Thus, the goal of the present study was to assess the knowledge and attitudes of patients with epilepsy toward their disease.
3. Methods
This study was permitted by the Ethics Committee of Mazandaran University of Medical Sciences.
3.1. Study Design and Location
A cross-sectional study was conducted from August 2016 to Jun 2018 in an outpatient clinic of a medical university (Tooba Clinic) in Sari city, the North of Iran. The clinic is a tertiary referral center for all urban and rural regions of Mazandaran Province, Iran, and a teaching clinic affiliated to the Mazandaran University of Medical Sciences.
3.2. Inclusion and Exclusion Criteria
The study sample included adult (≥ 18 years of age) patients with epilepsy for more than six months attending a neurology outpatient clinic for usual follow-ups. Patients who had single seizures were illiterate or had dementia, or other forms of non-epileptic neurological or psychological deficiency were excluded. With a confidence level of 95% and an error rate of 5%, a total of 155 PWE participated in this study.
3.3. Study Questionnaire and Measures
The questionnaire consisted of demographic data and closed-ended questions. Thirty-four questions were established after a widespread review of the literature (23-25). The questions were translated from English into Farsi and then back-translated by neurologists. Straightforwardness, truthfulness, and implication were attentively investigated. A pilot study was conducted on 25 randomly selected PWE with an interval of two weeks to corroborate the reliability and consistency of the Farsi version of the questionnaire. The reliability of the questionnaire was confirmed by Cronbach’s alpha, which gave rise to the internal consistency of 0.75. The sociodemographic characteristics consisted of age, sex, marital status, education, occupation, and the number of family members. The closed-ended questions included 14 questions about knowledge, 11 questions about attitudes, and nine questions about epilepsy knowledge profile-personal. The responses to the questions were either “yes,” “no,” or “I do not know.” The participants completed the questionnaires at an established time and place. The investigators would help the participants if there were any questions. The knowledge, attitude, and knowledge profile-personal of the patients were assessed individually for each participant. Each correct answer was given one point, while the wrong or “I do not know” responses scored zero. For the assessment of the total attitude and knowledge of the contributors, the scores were summed up for each participant. The score range was 0 - 14 for knowledge, 0 - 11 for attitudes, and 0 - 9 for epilepsy knowledge profile-personal. The level of knowledge and attitude was categorized based on the score or percentage of correct answers. Hence, the knowledge of patients was categorized as poor (0 - 7 or ≤ 50%), fair (8 - 10 or 51% - 75%), and good (11 - 14 or > 75%). The attitude score was categorized as either negative (0 - 6 or ≤ 50%) or positive (7 - 11 or > 51%). Further, the knowledge profile-personal score was considered either poor (0 - 5 or ≤ 50%) or good (6 - 9 or > 51%) (15, 23).
3.4. Statistical Analysis
The data were analyzed using SPSS version 22.0 (SPSS Inc., Chicago, IL, USA). The demographic information and epilepsy knowledge and attitudes were presented using descriptive statistics (mean, percentage, and frequency distribution). The chi-square (χ2) was used to determine the association between variables and demographic data. The results were considered significant at P < 0.05.
4. Results
The mean age of the participants was 31.73 ± 11.06 years (range: 16 - 65); 60% were female (mean age = 32.38 ± 10.95), and 40% were male (mean age = 30.75 ± 11.25). There was no significant difference in the age range between the genders. The majority of the participants (99 out of 155; 63.9%) were married. Concerning the education level, 69% of the participants had a diploma degree or college education. The demographic data are shown in Table 1.
| Variables | Values |
|---|---|
| Gender | |
| Male | 62 (40.0) |
| Female | 93 (60.0) |
| Age, y | |
| 18 - 28 | 59 (38.1) |
| 29 - 39 | 41 (26.5) |
| 40 - 50 | 41 (26.5) |
| > 50 | 14 (9.0) |
| Marital status | |
| Single | 5 (35.5) |
| Married | 99 (63.9) |
| Widowed or divorced | 1 (0.60) |
| Education level | |
| Primary school | 18 (11.6) |
| Secondary school | 30 (19.4) |
| Diploma | 67 (43.2) |
| University education | 40 (25.8) |
| Occupation | |
| Unemployed | 32 (20.6) |
| Employed | 18 (11.6) |
| Housewife | 64 (41.3) |
| Professional | 41 (36.5) |
| Number of members in the family | |
| < 3 | 45 (29.0) |
| 3 - 5 | 90 (58.1) |
| > 5 | 20 (12.9) |
4.1. Knowledge About Epilepsy
Regarding the cause of epilepsy, 85.8% of the participants reported that epilepsy is a brain disorder, while only 6.5% of the participants described that epilepsy is caused by demon possession or supernatural powers. In addition, in terms of factors provoking a seizure attack, 61.3%, 70.3%, and 53.5% of the patients mentioned that starvation, insomnia, and watching TV or working with a computer for the long run could cause seizures, respectively. The subjects’ knowledge about epilepsy is demonstrated in Table 2. In terms of the knowledge score, 12 (7.7%), 85 (54.8%), and 58 (37.4%) of the participants had poor, fair, and good knowledge about epilepsy, respectively. There was a significant relationship between the education level and knowledge about epilepsy. Accordingly, patients with university education had good knowledge about the disease (P = 0.007). However, there was no significant relationship between other demographic information and knowledge about epilepsy.
Epileptic Patients’ Knowledge Questionnaire
| Items | Yes (%) | No (%) | I Don’t Know (%) |
|---|---|---|---|
| 1) Do you think epilepsy is a hereditary disorder? | 37 (23.8) | 115 (74.2) | 3 (1.9) |
| 2) Do you think epilepsy is a disorder of the brain? | 133 (85.8) | 20 (12.9) | 2 (1.9) |
| 3) Do you think the cause of epilepsy is unknown? | 53 (34.2) | 99 (63.9) | 3 (1.9) |
| 4) Do you think epilepsy is caused by demon possession or supernatural powers | 10 (6.5) | 142 (91.6) | 3 (1.9) |
| 5) Do you think malnutrition is the cause of epilepsy? | 36 (23.2) | 115 (74.2) | 4 (2.6) |
| 6) Do you think epilepsy is an infectious disease and contagious? | 5 (3.2) | 148 (95.5) | 2 (1.3) |
| 7) Do you think epilepsy is a form of mental illness? | 72 (46.5) | 81 (52.3) | 2 (1.3) |
| 8) Do you think starvation can cause attacks of seizure in epileptic patients? | 95 (61.3) | 60 (38.7) | 0 (0) |
| 9) Do you think inadequate sleep can cause attacks of seizure in PWE? | 109 (70.3) | 41 (26.5) | 5 (3.2) |
| 10) Do you think some certain foods or drinks make a seizure attack? | 66 (42.6) | 87 (56.1) | 2 (3.2) |
| 11) Do you think watching the TV or working a computer for a long time can cause epileptic attacks? | 83 (53.5) | 71 (45.5) | 1 (0.6) |
| 12) Do you think epilepsy is more violent than? | |||
| (i) AIDS | 13 (8.4) | 138 (89) | 4 (2.6) |
| (ii) Malignant carcinoma | 28 (18.1) | 126 (81.3) | 1 (0.6) |
| (iii) Stroke | 55 (35.5) | 98 (83.2) | 2 (1.3) |
4.2. Attitude Toward Epilepsy
The majority of the respondents agreed that PWE could marry. Moreover, most of the patients had positive attitudes toward having appropriate occupations and college education. Nevertheless, more than half of the patients reported that PWE could drive and swim safely. Table 3 demonstrates the patients’ attitudes toward epilepsy. In general, 17.4% and 82.6% of the patients had negative and positive attitudes toward the disease based on the attitude score, respectively. Additionally, 89.7% of the responders mentioned that PWE could marry, 65.2% of whom had a diploma degree or higher education (P = 0.001). A significant relationship was observed between the education level and marital status (0.02). Moreover, 83.9% of the patients declared that PWE could find an appropriate occupation, and 91% of the participants stated that PWE could have a university education. These positive attitudes were associated with a high education level (P = 0.001).
Attitudes Toward Epilepsy
| Items | Yes (%) | No (%) | I Don’t Know (%) |
|---|---|---|---|
| 1) Do you think people with epilepsy can get married? | 139 (89.7) | 14 (9.0) | 2 (1.3) |
| 2) Do you think PWE can get pregnant? | 125 (80.6) | 24 (15.5) | 6 (3.9) |
| 3) Do you think PWE can drive safely? | 100 (64.5) | 55 (35.5) | 0 (0.0) |
| 4) Do you think PWE can swim alone? | 102 (65.8) | 52 (33.5) | 1 (0.6) |
| 5) Do you think PWE can get opportunities of appropriate occupation? | 130 (83.9) | 23 (14.8) | 2 (1.3) |
| 6) Do you think PWE may require lifelong treatment? | 78 (50.3) | 74 (47.7) | 3 (1.7) |
| 7) Do you think PWE can have a college education? | 141 (91.0) | 14 (9.0) | 0 (0.0) |
| 8) Do you think PWE are insane? | 4 (2.6) | 149 (96.1) | 2 (1.3) |
| 9) Do you think PWE have lower intelligence than other people have? | 15 (9.7) | 140 (90.3) | 0 (0.0) |
| 10) Do you think a cure is achievable by magic/religious practices? | 16 (10.3) | 138 (89.9) | 1 (0.6) |
| 11) Do you think PWE have to hide their illness? | 59 (38.1) | 96 (61.9) | 0 (0.0) |
4.3. Patient Knowledge Profile-Personal
In terms of patients’ self-assessment about their epilepsy, 60% of the patients recognized truthful names for their seizure types. In addition, 55.5% and 43.2% of the patients were aware of the results of their electroencephalograms and brain imaging, respectively. The majority of the patients (92.9%) were consuming antiepileptic medications according to the physicians’ instructions. However, most of the patients were unaware of the side effects of the medications during pregnancy and on the fetus. Table 4 shows the percentage of respondents based on the answer “yes” and “no”. In general, 50.3% of the patients had poor knowledge and 49.7% of them had good knowledge based on the patients’ knowledge profile-personal scores. In this study, a significant correlation was found between gender and knowledge profile-personal (P = 0.009).
Patient Knowledge Profile-Personal
| Items | Yes (%) | No (%) |
|---|---|---|
| 1) Do you know your seizure type? | 93 (60.0) | 62 (40.0) |
| 2) Do you know the results of your EEG assessment? | 86 (55.5) | 69 (45.5) |
| 3) Do you know the results of your brain imaging? | 67 (43.2) | 88 (56.8) |
| 4) Do you take antiepileptic drugs regularly according to the physician’s prescription? | 144 (92.9) | 11 (7.1) |
| 5) Do you know the side effects of antiepileptic drugs? | 67 (43.2) | 88 (56.8) |
| 6) Do you know the side effects of antiepileptic drugs on the fetus? | 45 (29.0) | 110 (71.0) |
| 7) Do patients with epilepsy have to use antiepileptic drugs only at the time of seizure attack? | 25 (16.1) | 130 (83.9) |
| 8) Have you ever acknowledged information about epilepsy? | 115 (74.2) | 40 (25.8) |
| 9) If yes, what resources did you have? | ||
| Physician | (55.5) | |
| Mass media | (7.7) | |
| Book | (11) |
5. Discussion
Overall, in our study, the patients’ knowledge about epilepsy was fair to good among people suffering from this disease. A vast majority of the participants were familiar with the causes of epilepsy. Moreover, the majority of the participants mentioned that the prominent cause of epilepsy was a brain disorder, while a few of them believed that epilepsy was contagious or caused by supernatural powers. These findings are similar to those of previous studies in Iran (15, 19, 21). Previous studies in Iran have been mostly conducted on specific community groups such as teachers, the general public, and first-degree relatives (15, 19, 21). Ghanean et al. (22) reported that public knowledge was good about epilepsy.
Moreover, a vast majority of the studies regarded a brain disease as the cause of epilepsy, and none blamed evil spirits (21). These results are different from those of other studies conducted in developing countries such as southwestern Nigeria, India, and China where the majority of the participants recognized epilepsy as a supernatural or mental illness (26-28). On the other hand, in the present study, nearly half of the participants believed that epilepsy was a mental illness, and one-fourth of the participants considered epilepsy as a malnutrition disorder. This misconception was also reported in previous studies in different countries (29-32). Differences observed in studies may be correlated with cultural variations or educational levels of the population surveyed.
In this study, proper awareness of epilepsy was associated with a high level of literacy. Accordingly, patients with higher education had higher epilepsy knowledge scores than those with lower education, as previously reported in other studies (33, 34). In addition, in the present study, more than half of the participants reported that inadequate sleep, watching TV, working with a computer for a long time, and starvation could increase the risk of seizure attacks, similar to the outcomes from other studies (15, 18, 29). However, studies are limited concerning the effect of starvation on seizure attacks. In response to questions on comparing epilepsy with other disorders, the majority of the participants believed that stroke, malignancy, and AIDS were more violent than epilepsy. Such beliefs are highly important in the psychosocial aspect because they help PWE to better control and manage their seizures. Further, the majority of the responders had positive attitudes toward epilepsy. They believed that PWE did not have lower intelligence than other people and could find appropriate occupations. The current study also revealed that PWE with a lower education level often had negative attitudes about epilepsy. Nevertheless, there were misconceptions about the driving and swimming capabilities of PWE. In Iran, patients with epilepsy cannot legally obtain a driving license, and this misconception may be harmful to patients. Moreover, patients are constantly warned about swimming without supervision. In our study, 61.1% of the responders mentioned that they hide their disease from others, which is a finding similar to other study results (17, 35). Aydemir et al. (35) reported that the reason for hiding epilepsy could be the fear of others’ attitudes and also the fear of discrimination. In the present study, more than half of the patients knew their seizure type correctly and were aware of their electroencephalography results. These results are similar to those of Coker et al.’s study (25). Most of the patients consumed antiepileptic drugs regularly but were not aware of their side effects. Overall, PWE had poor knowledge about their disease, which is similar to the results of Mameniskiene et al.'s study (33). In this regard, males had less knowledge about the disease than females. This finding is similar to those of Jacoby et al. and Spott et al.'s studies (36, 37). However, for more detailed analyses, larger sample sizes are required.
5.1. Conclusions
This study showed that despite the positive attitude toward epilepsy, good knowledge about the disease is still below 50%. Given that the majority of the patients were consuming antiepileptic medications according to the physician’s instructions, most of them were unaware of the side effects of the medications. Limited knowledge about epilepsy among PWE appears to be a feature related to their illness and can depend on the education level and culture. These results indicate that there is still a need for educational programs to raise epileptic patients’ awareness of their disease. Education to people with epilepsy and their families causes them to know misconceptions, promote the quality of life, and reduce concerns about stigma. This training should be provided by the health care system, especially epilepsy centers.
References
-
1.
WHO. Epilepsy. Geneva: World Health Organization; 2009.
-
2.
Ngugi AK, Bottomley C, Kleinschmidt I, Sander JW, Newton CR. Estimation of the burden of active and life-time epilepsy: A meta-analytic approach. Epilepsia. 2010;51(5):883-90. [PubMed ID: 20067507]. [PubMed Central ID: PMC3410521]. https://doi.org/10.1111/j.1528-1167.2009.02481.x.
-
3.
Fiest KM, Sauro KM, Wiebe S, Patten SB, Kwon CS, Dykeman J, et al. Prevalence and incidence of epilepsy: A systematic review and meta-analysis of international studies. Neurology. 2017;88(3):296-303. [PubMed ID: 27986877]. [PubMed Central ID: PMC5272794]. https://doi.org/10.1212/WNL.0000000000003509.
-
4.
Sayehmiri K, Tavan H, Sayehmiri F, Mohammadi I, V. Carson K. Prevalence of epilepsy in Iran: A meta-analysis and systematic review. Iran J Child Neurol. 2014;8(4):9-17. [PubMed ID: 25657765]. [PubMed Central ID: PMC4307363].
-
5.
Covanis A, Guekht A, Li S, Secco M, Shakir R, Perucca E. From global campaign to global commitment: The World Health Assembly's Resolution on epilepsy. Epilepsia. 2015;56(11):1651-7. [PubMed ID: 26391429]. https://doi.org/10.1111/epi.13192.
-
6.
Jacoby A. Epilepsy and the quality of everyday life. Soc Sci Med. 1992;34(6):657-66. https://doi.org/10.1016/0277-9536(92)90193-t.
-
7.
Kobau R, Price P. Knowledge of epilepsy and familiarity with this disorder in the U.S. population: Results from the 2002 HealthStyles Survey. Epilepsia. 2003;44(11):1449-54. [PubMed ID: 14636355]. https://doi.org/10.1046/j.1528-1157.2003.17603.x.
-
8.
Alem A. Mental health services and epidemiology of mental health problems in Ethiopia. Ethiop Med J. 2001;39(2):153-65. [PubMed ID: 11501293].
-
9.
Jacoby A. Stigma, epilepsy, and quality of life. Epilepsy Behav. 2002;3(6S2):10-20. [PubMed ID: 12609301]. https://doi.org/10.1016/s1525-5050(02)00545-0.
-
10.
de Boer HM, Mula M, Sander JW. The global burden and stigma of epilepsy. Epilepsy Behav. 2008;12(4):540-6. [PubMed ID: 18280210]. https://doi.org/10.1016/j.yebeh.2007.12.019.
-
11.
Guekht AB, Mitrokhina TV, Lebedeva AV, Dzugaeva FK, Milchakova LE, Lokshina OB, et al. Factors influencing on quality of life in people with epilepsy. Seizure. 2007;16(2):128-33. [PubMed ID: 17157536]. https://doi.org/10.1016/j.seizure.2006.10.011.
-
12.
Bautista RE, Wludyka P. Factors associated with employment in epilepsy patients. Epilepsy Behav. 2007;10(1):89-95. [PubMed ID: 17118712]. https://doi.org/10.1016/j.yebeh.2006.10.006.
-
13.
Senol V, Soyuer F, Arman F, Ozturk A. Influence of fatigue, depression, and demographic, socioeconomic, and clinical variables on quality of life of patients with epilepsy. Epilepsy Behav. 2007;10(1):96-104. [PubMed ID: 17097354]. https://doi.org/10.1016/j.yebeh.2006.08.006.
-
14.
Lua PL, Nor-Khaira-Wahida K, Zariah AA, Lee KF. Caregiving for epilepsy: Awareness, knowledge, attitude and health-related quality of life of family caregivers. Malays J Psychiatry. 2014;23(1):45-56.
-
15.
Karimi N, Akbarian SA. Knowledge and attitude toward epilepsy of close family members of people with epilepsy in North of Iran. Adv Med. 2016;2016:8672853. [PubMed ID: 28116347]. [PubMed Central ID: PMC5220387]. https://doi.org/10.1155/2016/8672853.
-
16.
Ghanean H, Jacobsson L, Nojomy M. Self-perception of stigma in persons with epilepsy in Tehran, Iran. Epilepsy Behav. 2013;28(2):163-7. [PubMed ID: 23747500]. https://doi.org/10.1016/j.yebeh.2013.04.009.
-
17.
Neyaz HA, Aboauf HA, Alhejaili ME, Alrehaili MN. Knowledge and attitudes towards epilepsy in Saudi families. J Taibah Univ Med Sci. 2017;12(1):89-95. [PubMed ID: 31435221]. [PubMed Central ID: PMC6695036]. https://doi.org/10.1016/j.jtumed.2016.06.007.
-
18.
Yeni K, Tulek Z, Bebek N, Dede O, Gurses C, Baykan B, et al. Attitudes towards epilepsy among a sample of Turkish patients with epilepsy. Epilepsy Behav. 2016;62:66-71. [PubMed ID: 27450308]. https://doi.org/10.1016/j.yebeh.2016.06.022.
-
19.
Smithson WH, Hukins D, Buelow JM, Allgar V, Dickson J. Adherence to medicines and self-management of epilepsy: A community-based study. Epilepsy Behav. 2013;26(1):109-13. [PubMed ID: 23246201]. https://doi.org/10.1016/j.yebeh.2012.10.021.
-
20.
Karimi N, Heidari M. Knowledge and attitudes toward epilepsy among school teachers in West of Iran. Iran J Neurol. 2015;14(3):130-5. [PubMed ID: 26622977]. [PubMed Central ID: PMC4662685].
-
21.
Masoudnia E. Awareness, understanding and attitudes towards epilepsy among Iranian ethnic groups. Seizure. 2009;18(5):369-73. [PubMed ID: 19223209]. https://doi.org/10.1016/j.seizure.2009.01.009.
-
22.
Ghanean H, Nojomi M, Jacobsson L. Public awareness and attitudes towards epilepsy in Tehran, Iran. Glob Health Action. 2013;6:21618. [PubMed ID: 24314322]. [PubMed Central ID: PMC3855600]. https://doi.org/10.3402/gha.v6i0.21618.
-
23.
Kabir M, Iliyasu Z, Abubakar IS, Kabir ZS, Farinyaro AU. Knowledge, attitude and beliefs about epilepsy among adults in a northern Nigerian urban community. Ann Afr Med. 2005;4(3):107-12.
-
24.
Long L, Reeves AL, Moore JL, Roach J, Pickering CT. An assessment of epilepsy patients' knowledge of their disorder. Epilepsia. 2000;41(6):727-31. [PubMed ID: 10840406]. https://doi.org/10.1111/j.1528-1157.2000.tb00235.x.
-
25.
Coker MF, Bhargava S, Fitzgerald M, Doherty CP. What do people with epilepsy know about their condition? Evaluation of a subspecialty clinic population. Seizure. 2011;20(1):55-9. [PubMed ID: 21093304]. https://doi.org/10.1016/j.seizure.2010.10.007.
-
26.
Choi-Kwon S, Kim EK, Youn SM, Choi JM, Lee SK, Chung CK. Common misconceptions in people with epilepsy. J Clin Neurol. 2006;2(3):186-93. [PubMed ID: 20396505]. [PubMed Central ID: PMC2854963]. https://doi.org/10.3988/jcn.2006.2.3.186.
-
27.
Samant JM, Lala VM, Ravindranath S, Desai AD. Social aspects of epilepsy. Neurol India. 1973;21:165-74.
-
28.
Sunmonu TA, Afolabi OT, Komolafe MA, Ogunrin AO. Patients' knowledge about their disorder: Perspective of patients with epilepsy in a tertiary health facility in southwestern Nigeria. Epilepsy Behav. 2011;20(3):556-60. [PubMed ID: 21277835]. https://doi.org/10.1016/j.yebeh.2010.12.030.
-
29.
Saengsuwan J, Laohasiriwong W, Boonyaleepan S, Sawanyawisuth K, Tiamkao S; Integrated Epilepsy Research Group. Knowledge, attitudes, and care techniques of caregivers of PWE in northeastern Thailand. Epilepsy Behav. 2013;27(1):257-63. [PubMed ID: 23453636]. https://doi.org/10.1016/j.yebeh.2013.01.014.
-
30.
Tran DS, Odermatt P, Singphuoangphet S, Druet-Cabanac M, Preux PM, Strobel M, et al. Epilepsy in laos: Knowledge, attitudes, and practices in the community. Epilepsy Behav. 2007;10(4):565-70. [PubMed ID: 17446140]. https://doi.org/10.1016/j.yebeh.2007.02.018.
-
31.
Yoo JK, Jung KY, Park KW, Lee DH, Lee SK, Lee IK, et al. Familiarity with, understanding of, and attitudes toward epilepsy among people with epilepsy and healthy controls in South Korea. Epilepsy Behav. 2009;16(2):260-7. [PubMed ID: 19695960]. https://doi.org/10.1016/j.yebeh.2009.07.025.
-
32.
Saengsuwan J, Boonyaleepan S, Srijakkot J, Sawanyawisuth K, Tiamkao S; Integrated Epilepsy Research Group. Factors associated with knowledge and attitudes in persons with epilepsy. Epilepsy Behav. 2012;24(1):23-9. [PubMed ID: 22503426]. https://doi.org/10.1016/j.yebeh.2012.03.006.
-
33.
Mameniskiene R, Sakalauskaite-Juodeikiene E, Budrys V. People with epilepsy lack knowledge about their disease. Epilepsy Behav. 2015;46:192-7. [PubMed ID: 25847428]. https://doi.org/10.1016/j.yebeh.2015.03.002.
-
34.
Ak PD, Atakli D, Yuksel B, Guveli BT, Sari H. Stigmatization and social impacts of epilepsy in Turkey. Epilepsy Behav. 2015;50:50-4. [PubMed ID: 26117273]. https://doi.org/10.1016/j.yebeh.2015.05.014.
-
35.
Aydemir N, Ozkara C, Unsal P, Canbeyli R. A comparative study of health related quality of life, psychological well-being, impact of illness and stigma in epilepsy and migraine. Seizure. 2011;20(9):679-85. [PubMed ID: 21764337]. https://doi.org/10.1016/j.seizure.2011.06.017.
-
36.
Jacoby A, Gorry J, Gamble C, Baker GA. Public knowledge, private grief: A study of public attitudes to epilepsy in the United Kingdom and implications for stigma. Epilepsia. 2004;45(11):1405-15. [PubMed ID: 15509242]. https://doi.org/10.1111/j.0013-9580.2004.02904.x.
-
37.
Spatt J, Bauer G, Baumgartner C, Feucht M, Graf M, Mamoli B, et al. Predictors for negative attitudes toward subjects with epilepsy: A representative survey in the general public in Austria. Epilepsia. 2005;46(5):736-42. [PubMed ID: 15857441]. https://doi.org/10.1111/j.1528-1167.2005.52404.x.