Effects of Black Scorpion Androctonus crasicuda Venom on Striated Muscle Preparation in vitro.

authors:

avatar Hossein Vatanpour 1 , *

Department of Pharmacology and Toxicology, School of Pharmacy, Shaheed Beheshti University of Medical Sciences
Iranian Journal of Pharmaceutical Research: Vol.2, issue 1; 17-22
published online: November 20, 2010
article type: Research Article
received: May 01, 2002
accepted: February 01, 2003
DOI: https://doi.org/10.22037/ijpr.2010.29

how to cite: Vatanpour H. Effects of Black Scorpion Androctonus crasicuda Venom on Striated Muscle Preparation in vitro.. Iran J Pharm Res. 2003;2(1):e127603. https://doi.org/10.22037/ijpr.2010.29.

Abstract

Effects of venom from black scorpion Androctonus crasicuda (AC) were determined on isolated chick biventer cervices nerve-muscle and mouse hemidiaphragm preparations using twitch tension method. The isolated nerves were stimulated by electrical stimulator and response to each stimulus was recorded. The venom mainly acted prejunctionally to facilitate neuromuscular activity due to an increase in acetylcholine release.