IJ Pharmaceutical Research
5
Aug
2025
Research Article
Low-Dose Celastrol Modulates IL-6 Secretion to Overcome Resistance to Sorafenib in Hepatocellular Carcinoma Cells
Rui Zhang
*,
*,Lingchun Kong,
Hezhao Zhang,
Anhong Zhang,
Zhiyong Shi,
Pei Wei**
**3
Aug
2025
Research Article
Assessing the Challenges of Managing Pharmacy Services in Public Hospitals in Erbil City
Sanar Ilias Kamal*,
*,Kemal M Surji
28
Jul
2025
Research Article
Chronic Pseudomonas aeruginosa Pneumonia Triggers Inflammation-Driven Oncogenic Signaling in Juvenile Mice: Implications for Pharmacological Intervention
Jing Zhang,
Zahra Zahid Piracha,
Umar Saeed,
Dilber Uzun Ozsahin,
Muhammad Waseem,
Yale Zhang*
27
Jul
2025
Research Article
Evaluation of the Rational Use of Broad-Spectrum Antibiotics According to Regulatory Guidelines in Hospitalized Patients: A Descriptive Study
Alireza Kananinambani,
Majid Shohrati*,
Mahdi Bagheri,
Bita Najafian
26
Jul
2025
Research Article
Schisanhenol Alleviates Mycophenolic Acid-Induced Intestinal Epithelial Cell Barrier Damage by Activating the Nrf2/HO-1 Signaling Pathway
Yiyun Deng,
Jiawang Fan,
Chunlan Yang,
Yan Huang,
Qingrong Xia,
Jun Liang
,et al.21
Jul
2025
Brief Report
Cancer-Associated Fibroblasts Enhance Oxaliplatin Resistance in Colorectal Cancer Cells via Paracrine IL-6: An In Vitro Study
Jiahui Wang,
Yanxin Lu,
Zhiyong Wang*,
*,Pei Wei**
**16
Jul
2025
Research Article
Effect of Diamorphine on Spatial Learning and Memory and Mitochondrial Function of Male Rat Brain
Ainaz Moshtagh,
Maryam Mehdizadeh,
Ghodsieh Hosseinifakhr,
Alireza Foroumadi,
Maryam Baeeri,
Shokoufeh Hassani
,et al.13
Jul
2025
Research Article
Anti-tumor Effects of Hedyotis diffusa Willd on Cervical Cancer: Inhibition of Proliferation, Migration, and Induction of Apoptosis
Siyu Yang,
Lizhu Zeng,
Caiyun Deng,
Xianglian Tian,
Wenkui Sun,
Chengjie Ji*
,et al.8
Jul
2025
Research Article
Role of Arctium lappa L. Root (Burdock) Extract in CFA-induced Arthritis Rat Model: Impact on Antioxidant Activity and Inflammation
Mohammad Hosein Farzaei,
,Arezoo Moini Jazani,
,Mina Salimi,
,Sahar Shafiei,
,Hosna Khazaei,
,Mohammad Hashemnia
,et al.29
Jun
2025
Research Article
Minocycline Regulates PARP-1 and HDAC3 Pathways to Inhibit Inflammation and Oxidative Stress in LPS-Induced Acute Lung Injury
Chao Luo,
,Xixi Zhu,
Jiefei Liang,
,Chunyan Zhu,
Guohua Shen,
Weibin Wu*
*29
Jun
2025
Research Article
Investigation of Peppermint (Mentha piperita) Extract on the Inhibition of Biofilm Formation by Acinetobacter baumannii Strains Isolated from Clinical Samples
Zahra Majidi Fard,
,Negin Irani Mavi,
,Shokoofeh Akbari,
,Yousef Erfani*,
*,Sanaz Eghtedari
26
May
2025
Research Article
Cannabidiol Extracted from Cannabis sativa L. Plant Shows Neuroprotective Impacts Against 6-HODA-Induced Neurotoxicity via Nrf2 Signal Transduction Pathway
Afsaneh Esfandi,
Ali Mehrafarin*,
*,Sepideh Kalateh Jari,
,Hassanali Naghdi Badi,
,Kambiz Larijani
25
May
2025
Review Article
AI-Powered Insights into Drug Resistance in Gastric Cancer: A Path Toward Precision Therapy
Negar Mottaghi-Dastjerdi*,
*,Mohammad Soltany-Rezaee-Rad
20
May
2025
Research Article
Resveratrol Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion by Targeting Lingo-1, NgR1, p75, and RhoA/ROCK-2 Pathways
Mohabbat Jamhiri,
Fatemeh Safari,
Jalil Alizadeh Ghalenoei,
Fatemeh Zare Mehrjerdi*,
Mansoureh Eslami**
29
Apr
2025
Research Article
Selective Toxicity of Iron, Manganese Oxide Nanostructure and Laser Wave on Colorectal and Breast Cancer Cell
Aysan Mansournia,
Nasim Nobari*,
Fatemeh Ghanbary,
,Behrooz Khezri
19
Apr
2025
Research Article
Comparison of Pharmacokinetic/Pharmacodynamic Parameters and Clinical Outcomes of Vancomycin Administered in Two Different Dosage Regimens in Patients with Acute Kidney Injury
Rokhsareh Soufi,
,Jamshid Salamzadeh,
Ilad Alavi Darazam,
,Mahdi Amirdosara,
,Masood Zangi,
Minoosh Shabani
,et al.16
Apr
2025
Brief Report
Acetylenic Metabolites and a 2-Phenoxychromone Derivative from the Aerial Parts of Artemisia biennis
Maryam Najafi,
Yalda Shokoohinia,
,Mahdi Mojarrab*
*14
Apr
2025
Research Article
Evaluation of Antimicrobial Activity of Novel Chimeric M-PEX12 Peptide Against Acinetobacter baumannii
Yasin Rakhshani,
Hamideh Mahmoodzadeh Hosseini,
,Seyed Ali Mirhosseini,
Fatah Sotoodehnejadnematalahi,
Jafar Amani*
*14
Apr
2025
Research Article
Investigation of the Antioxidant and Cellular Toxicity Activities of Gold Nanoparticles Synthesized Using Cichorium intybus Extract on a Liver Cancer Cell Line
Mohammad Mohammad-Alizadeh,
Ahmad Asgharzadeh*,
Maryam Tatari
13
Apr
2025
Research Article
Study on the Role of Schisandrin B in Ameliorating Hepatic Ischemia-Reperfusion Injury by Modulating Hepatocyte Autophagy
Zhao Fei,
Pan Haihang,
Chen Xueyang,
Shen Miao*
3
Apr
2025
Research Article
Pharmacokinetics and Bioequivalence of Two Formulations of Apixaban Tablets: A Double-Blind, Single-Dose, Crossover Study in Healthy Subjects
Erfan Abdollahizad,
Azadeh Haeri*,
*,Abolghasem Jouyban,
Mohammad Reza Afshar Mogaddam,
Zahra Abbasian,
Simin Dadashzadeh**
**26
Mar
2025
Research Article
Antimicrobial, Anti-inflammatory, Angiogenesis, and Wound Healing Activities of Copper Nanoparticles Green Synthesized by Lupinus arcticus Extract
Nizar H. Saeedi*,
Abdullah D. Alanazi,
Rawaf Alenazy,
Abdullah F. Shater
15
Mar
2025
Research Article
Design, Synthesis, and Evaluation of Cytotoxic Effects of Functional Fatty Acid Derivatives as Potential Antineoplastic Agents for Breast Cancer
Maryam Hosseini,
,Farzad Kobarfard*,
*,Salimeh Amidi**,
**,Shaya Mokhtari,
Anna Sedaghat,
Soraya Shahhosseini
9
Mar
2025
Research Article
Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9
Nigar Houssein-Zadeh,
Leila Sadeghi*,
*,Gholamreza Dehghan
9
Mar
2025
Research Article
Development of a Potential Bone-Seeking Radiopharmaceutical by Sodium Pyrophosphate Labeled 188Rhenium (188Re-PYP) for Bone Pain Palliation
Mahmoud Moradi,
Mehdi Salehi Barough*,
*,Leila Moghaddam-Banaem**,
Fariba Johari Daha,
Sahar Rajabi-Moghadam
8
Mar
2025
Research Article
Neuroprotective Effects of Early TLR4 Blockade with Compound C34 in Temporal Lobe Epilepsy: Alleviation of Neuroinflammation and Apoptosis
Roya Varmazyar,
Nima Naderi,
Hanieh Javid,
Rasoul Ghasemi,
Hamid Gholami Pourbadie*
8
Mar
2025
Research Article
KMT2D Induces M1 Macrophage Polarization to Repress Non-small Cell Lung Cancer Progression via Transcription Activation of ITGAL
Wen-Tao Wang,
Jie Yang,
Peng-Fei Jiang*
2
Mar
2025
Research Article
Design, Synthesis, Anticonvulsant Evaluation, and Molecular Docking Studies of New GABAA Agonist Derivatives
Mansur Nassiri Koopaei,
Parsa Moghimirad,
Ebrahim Saeedian Moghadam,
Nasrin Nassiri Koopaei,
Massoud Amanlou,
Tahmineh Akbarzadeh
,et al.2
Mar
2025
Research Article
Neurobehavioral and Dopaminergic Dysfunctions Induced by Mixed Metal Exposure in C57BL/6 Mice
Daeun Lee,
,Haesoo Kim,
,Sarita Pyatha,
Kisok Kim*
*24
Feb
2025
Research Article
Evaluating The Therapeutic Effect of 2-Nitroimidazole on Toxoplasma gondii: An In vitro and In vivo Study Using BALB/c Mice
Elaheh Ghiasipour,
Javid Sadraei*,
*,Fatemeh Ghaffarifar
24
Feb
2025
Research Article
Synthesis and Bioactivity Investigation of Novel 2-({2-[(Dialkylamino) Methyl] Quinazolin-4-one-3-yl} Methyl) Benzonitrile Derivatives as Dipeptidyl Peptidase-4 Inhibitory Agent
Arif Arrahman,
,Noer Luthfianeu Edsyah,
Theresia Thiofani,
Hanifah Sakinatun Khalidah,
Laila Fauziah,
Anjani Widyasintia
,et al.22
Feb
2025
Research Article
Design and Characterization of Ricin Based Immunotoxins Against EPHA2 Receptor for Breast Cancer Therapy: An In-Silico Study
Atefeh Faraz,
,Jafar Amani*,
*,Sedigheh Arbabian,
,Shohreh Zare Karizi,
,Maryam Bikhof Torbati
22
Feb
2025
Research Article
Genistein Exerts Anti-proliferative Effects by Regulating Apoptosis and Autophagy-Related Genes and MicroRNAs in Human Urinary Bladder Neoplasm EJ138 Cells: An Experimental and Bioinformatic Study
Alireza Ziyabakhsh,
,Mohammad Amin Vatankhah,
,Farid Pakizeh,
,Ali Nosrat,
,Pouria Sobhi,
Mohammad Vakili Ojarood*
,et al.*15
Feb
2025
Research Article
Assessment of the Efficacy and Safety of Sublingual Melatonin on Symptom Severity, Quality of Life, and Sleep Disorders in Patients with Irritable Bowel Syndrome
Shabnam Shahrokh,
,Niloofar Namazi,
Mohammad Abbasinazari*,
Ali Abazarikia,
Amir Sadeghi,
,Arash Mahboubi
12
Feb
2025
Research Article
Combinatorial Effects of Chrysin with Doxorubicin, 5-Fluorouracil, and Cyclophosphamide on Triple-Negative Breast Cancer Cell Line
Sedighe Yosefi,
,Hamid Madanchi,
,Abbas Pakdel*,
*,Parviz Kokhaei,
,Maral Hemati,
,Negar Sarmadi
,et al.11
Feb
2025
Research Article
Perioperative Use of Pregabalin vs. Duloxetine for Pain Management of Knee Fracture Surgery: A Double-Blind Randomized Clinical Trial
Mohadeseh Masoumi,
Mohammad Soleimani,
Tara Shekari,
Maryam Alaei,
Mehrdad Sheikhvatan,
Mojtaba Mojtahedzadeh
,et al.10
Feb
2025
Research Article
The Protective Effects of Mitochondrial Therapy Against Vincristine- Induced Nephrotoxicity in the Rat’s Renal Proximal Tubular Cells
Armaghan Lohrasbi,
,Abdollah Arjmand,
Farzaneh Kamranfar,
Mehdi Aghsami*,
Jalal Pourahmad**
**9
Feb
2025
Letter
5-Alpha Reductase Inhibitors on Hypersexuality During the Manic Phase of Bipolar and Psychotic Patients; New Insight to a Well-Known Medicines
Mitra Mahmoudi Meymand,
,Saeed Mohammad Soleymani,
,Hadi Esmaily*
*8
Feb
2025
Review Article
Therapeutic Mechanisms of Phenothiazine Drugs: A Mini-Review of Advances in Cancer Treatment and Antibiotic Resistance
Xuewei Zou*,
*,Bai Xie
4
Feb
2025
Review Article
Curcumin as a Natural Therapeutic Agent: A Rapid Review of Potential Clinical Uses and Mechanisms of Action
Mohammad Mohajeri,
Reza Momenai,
,Somayyeh Karami-Mohajeri,
Mandana Ohadi*,
Mohammad Amin Raeisi Estabragh**
**2
Nov
2024
Research Article
Effect of Micronized Purified Flavonoid Fraction Containing Hesperidin and Diosmin on Vincristine-Induced Neuropathy in Rats; the Role of Nitric Oxide Pathway
Nikoo Abharian,
Nima Naderi,
,Noushin Nikray,
Mona Khoramjouy,
,Shokoofe Noori,
Hamed Shafaroodi
,et al.29
Jan
2025
