Clinical Effects of Fennel Essential oil on Primary Dysmenorrhea

authors:

avatar Nahid Khorshidi 1 , * , avatar Seyed Nasser Ostad 1 , avatar Mahmoud Mosaddegh 2 , avatar Malihe Soodi 3

Department of Gynecology & Obstetrics, School of Medicine, Iran University of Medical Sciences and Health Services, Tehran, Iran
Department of Toxicology & Pharmacology, School of Pharmacy, Tehran University of Medical Sciences and Health Services, Tehran, Iran
Traditional Medicine and Materia Medica Research Center (TMRC), Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Iran
Iranian Journal of Pharmaceutical Research: Vol.2, issue 2; 89-93
published online: November 20, 2010
article type: Research Article
received: November 01, 2002
accepted: May 01, 2003
DOI: https://doi.org/10.22037/ijpr.2010.18

how to cite: Khorshidi N, Ostad S N, Mosaddegh M, Soodi M. Clinical Effects of Fennel Essential oil on Primary Dysmenorrhea. Iran J Pharm Res. 2003;2(2):e127617. https://doi.org/10.22037/ijpr.2010.18.

Abstract

Dysmenorrhea is among the most common gynecological complaints. There are several mechanisms which initiate dysmenorrhea. Therefore, different compounds can be employed to control its symptoms. NSAIDs such as ibuprofen are highly used in modern medicine to relieve the pain in short-term therapy. This method is not acceptable for long-term therapy due to side effects. Our previous data showed that Fennel essential oil (FEO) could reduce the frequency and intensity of contraction of rat uterus in isolated organ models. Furthermore, the use of FEO is strongly recommended in traditional medicine for the relief of dysmenorrhea symptoms. Clinical study of FEO in primary dysmenorrhea showed that the essence reduces pain and some of following sequelae side effects noticeably.