Survey of fumonisin B1 contamination of cornin Northern Iran during 2000

authors:

avatar Hasan Yazdanpanah 1 , 2 , * , avatar Parvin Eskandari Gheidari 1 , avatar Afshin Zarghi 3 , avatar Seyed Karim Mirkarimi 4

Pharmacology and Toxicology Department, School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Iran
Pharmaceutical Research Center, Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Iran
Medicinal Chemistry Department, School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services, Tehran, Iran
Food and Drug Control Labs, Ministry of Health and Medical Education, Tehran, Iran
Iranian Journal of Pharmaceutical Research: Vol.4, issue 4; 221-225
published online: November 20, 2010
article type: Research Article
received: March 20, 2005
accepted: July 20, 2005
DOI: https://doi.org/10.22037/ijpr.2010.640

how to cite: Yazdanpanah H, Eskandari Gheidari P, Zarghi A, Mirkarimi S K. Survey of fumonisin B1 contamination of cornin Northern Iran during 2000. Iran J Pharm Res. 2005;4(4):e128248. https://doi.org/10.22037/ijpr.2010.640.

Abstract

Fumonisin B1 (FB1) is the most abundant of the fumonisin mycotoxins, mainly produced in corn by fungi of the genus Fusarium. FB1 has been shown to be hepatocarcinogenic and nephrocarcinogenic in animals. Contamination of corn with FB1 was assayed in samples collected from Mazandaran Province, situated on the Caspian littoral of Iran, in September 2000. In this survey, 38 corn samples were analyzed using HPLC, and all except one showed high levels of FB1 contamination ranged between 1.19 and 12.95 mg/kg. These results confirm the relatively high levels of FB1 contamination in corn of Mazandaran Province.