In Vitro Antihelmintic Property of Various Seed Oils

authors:

avatar Sunil S. Jalalpure 1 , * , avatar Kallanagoda R. Alagawadi 1 , avatar Channabasappa S. Mahajanshetty 1 , avatar Mahmad Salahuddin 2 , avatar Biren Shah 2

Department of Pharmaceutical Chemistry, KLES’s College of Pharmacy, Belguam- 590 010, Karnataka, India
Department of Pharmacognosy and Phytochemistry, KLES’s College of Pharmacy, Belguam-590 010, Karnataka, India

how to cite: Jalalpure S S, Alagawadi K R, Mahajanshetty C S, Salahuddin M, Shah B. In Vitro Antihelmintic Property of Various Seed Oils. Iran J Pharm Res. 2006;5(4):e128300. https://doi.org/10.22037/ijpr.2010.690.

Abstract

Seed oils of Passiflora edulis, Jatropa curucas, Tinospora cordifolia, Sesbania grandiflora and Sapindus laurifolia were investigated for their antihelmintic property against Pheritima pasthuma. Three concentrations (10, 50 and 100 mg/ml) of each oil were studied in the bioassay, which involved the determination of time of paralysis and time of death of the worm. Sesbania grandiflora showed the highly significant antihelmintic activity in both the parameters (paralysis and death), while Tinospora cordifolia showed significant effect in case of time of death. Piperazine citrate (10 mg/ml) was included in the assay as standard reference drug.