Shelf Life Prediction of Infant Formula by Using Rancidity Test

authors:

avatar Behrooz Jannat 1 , avatar Mohammad Reza Oveisi 2 , avatar Naficeh Sadeghi 2 , * , avatar Abdolazim Behfar 3 , avatar Mannan Hajimahmoodi 2 , avatar Forouzandeh Jannat 4 , avatar Sahar Khoshnamfar 2

Food and Drug Laboratory Research Center, Food and Drug Deputy, Ministry of Health and Medical Education, Tehran, Iran
Drug and Food Control Department, Faculty of Pharmacy, Tehran University of Medical Sciences
Bromatology Department, Faculty of Pharmacy, Ahvaz University of Medical Sciences
Arash Hospital, Tehran University of Medical Sciences

how to cite: Jannat B, Oveisi M R, Sadeghi N, Behfar A, Hajimahmoodi M, et al. Shelf Life Prediction of Infant Formula by Using Rancidity Test. Iran J Pharm Res. 2008;7(4):e128601. https://doi.org/10.22037/ijpr.2010.775.

Abstract

Infant formula has a fatty acid composition that meets the needs of the neonates for unsaturated fatty acids.These fatty acids are of major importance during this period of life in which the brain and retina are developing, and will therefore have an influence upon visual acuity and learning abilities.

Oxygen reacts readily with unsaturated fatty acids, so that every time these compounds are handled there is a danger of contaminated with oxidative products. Oxidative stability is an important parameter in characterization of fats and oils.

The purpose of this study was to predict the shelf life of an infant formula using accelerated stability test (rancimat), to save time. The Rancimat method is based on conductometric determination of volatile degradation products and features automatic plotting of the conductivity against time. The evaluation was performed graphically after completion of the experiments.

The stability of a commercially available infant formula in Tehran, Iran was measured using rancimat method at temperatures of 60, 80, 90, 100, 110, 120 and 130 °C.

Equations have been derived by which the shelf life can be predicted on the basis of the Rancimat method, thus avoiding the time-consuming long-term studies. The shelf life of the commercial infant formula studied was estimated as 534 days (approximately 18 months).