The Contents of Sesamol in Iranian Sesame Seeds

authors:

avatar Naficeh Sadeghi 1 , avatar Mohammad Reza Oveisi 1 , avatar Mannan Hajimahmoodi 1 , avatar Behrooz Jannat 2 , * , avatar Masoomeh Mazaheri 1 , avatar Sadollah Mansouri 3

Drug and Food Control Department, Faculty of Pharmacy, Medical Sciences/University of Tehran, Tehran, Iran
Food and Drug Laboratory Research Center, Ministry of Health and Medical Education, Tehran, Iran
Seed and Plant Improvement Institute, Karaj, Iran
Iranian Journal of Pharmaceutical Research: Vol.8, issue 2; 101-105
published online: November 20, 2010
article type: Research Article
received: April 01, 2008
accepted: October 01, 2008
DOI: https://doi.org/10.22037/ijpr.2010.796

how to cite: Sadeghi N, Oveisi M R, Hajimahmoodi M, Jannat B, Mazaheri M, et al. The Contents of Sesamol in Iranian Sesame Seeds. Iran J Pharm Res. 2009;8(2):e128623. https://doi.org/10.22037/ijpr.2010.796.

Abstract

Sesamol is a sesame lignan. Sesame lignans have multiple functions, including antioxidant activity and also seem to have potential as a source of phytostrogens. This study was condncted to evaluate sesamol contents of 7 brands of Iranian sesame seeds (Sesamum indicume L.). The brands were named Karaj 29, Darab 14, Ultan, Dezful, Varamin, Branching Naz, and Nonbranching Naz. After method validation, the methanolic extracts of seeds were investigated by HPLC. Their mean of total sesamol was found to be 4.67±0.92 mg/g (ranging between 2.75 and 6.13 mg/g). The brands Karaj 29 with 5.84±0.25 mg/g, Dezful with 5.48±0.08 mg/g, and Varamin with 5.4±0.1mg/g had the highest content, and Darab 14 with the content of 3.30±0.57mg/g had the lowest (p<0.05). Iranian sesame can be considered to be a good source of natural antioxidants for medicinal and commercial uses.