The Contents of Sesamol in Iranian Sesame Seeds

Naficeh Sadeghi; Mohammad Reza Oveisi; Mannan Hajimahmoodi; Behrooz Jannat; Masoomeh Mazaheri; Sadollah Mansouri

doi:10.22037/ijpr.2010.796

IJ Pharmaceutical Research

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https://doi.org/10.22037/ijpr.2010.796

The Contents of Sesamol in Iranian Sesame Seeds

Author(s):

Naficeh Sadeghi¹,

Mohammad Reza Oveisi¹,

Mannan Hajimahmoodi¹,

Behrooz Jannat^2,*,

Masoomeh Mazaheri¹,

Sadollah Mansouri³

1Drug and Food Control Department, Faculty of Pharmacy, Medical Sciences/University of Tehran, Tehran, Iran

2Food and Drug Laboratory Research Center, Ministry of Health and Medical Education, Tehran, Iran

3Seed and Plant Improvement Institute, Karaj, Iran

IJ Pharmaceutical Research:Vol. 8, issue 2; 101-105

Published online:Nov 20, 2010

Article type:Research Article

Received:Apr 01, 2008

Accepted:Oct 01, 2008

How to Cite:Naficeh SadeghiMohammad Reza OveisiMannan HajimahmoodiBehrooz JannatMasoomeh MazaheriSadollah Mansouriet al.The Contents of Sesamol in Iranian Sesame Seeds.Iran J Pharm Res.8(2):e128623.https://doi.org/10.22037/ijpr.2010.796.

Abstract

Sesamol is a sesame lignan. Sesame lignans have multiple functions, including antioxidant activity and also seem to have potential as a source of phytostrogens. This study was condncted to evaluate sesamol contents of 7 brands of Iranian sesame seeds (Sesamum indicume L.). The brands were named Karaj 29, Darab 14, Ultan, Dezful, Varamin, Branching Naz, and Nonbranching Naz. After method validation, the methanolic extracts of seeds were investigated by HPLC. Their mean of total sesamol was found to be 4.67±0.92 mg/g (ranging between 2.75 and 6.13 mg/g). The brands Karaj 29 with 5.84±0.25 mg/g, Dezful with 5.48±0.08 mg/g, and Varamin with 5.4±0.1mg/g had the highest content, and Darab 14 with the content of 3.30±0.57mg/g had the lowest (p<0.05). Iranian sesame can be considered to be a good source of natural antioxidants for medicinal and commercial uses.

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Author(s):

Naficeh Sadeghi:[PubMed][Scholar]
Mohammad Reza Oveisi:[PubMed][Scholar]
Mannan Hajimahmoodi:[PubMed][Scholar]
Behrooz Jannat:[PubMed][Scholar]
Masoomeh Mazaheri:[PubMed][Scholar]
Sadollah Mansouri:[PubMed][Scholar]