Badrakemonin, a New Eremophilane-Type Sesquiterpenefrom the Roots of Ferula badrakema Kos.-Pol.

authors:

avatar Mehrdad Iranshahi 1 , * , avatar Maral Ghiadi 2 , avatar Amirhossein Sahebkar 2 , avatar Atena Rahimi 2 , avatar Carla Bassarello 3 , avatar Sonia Piacente 3 , avatar Cosimo Pizza 3

Department of Pharmacognosy, Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
Dipartimento di Scienze Farmaceutiche, Università Degli Studi di Salerno, Via Ponte Don Melillo, 84084, Salerno, Italy

How To Cite Iranshahi M, Ghiadi M, Sahebkar A, Rahimi A, Bassarello C, et al. Badrakemonin, a New Eremophilane-Type Sesquiterpenefrom the Roots of Ferula badrakema Kos.-Pol.. Iran J Pharm Res. 2009;8(4):e128649. https://doi.org/10.22037/ijpr.2010.822.

Abstract

Phytochemical investigation of the dichloromethane extract of the dried roots of Ferula badrakema resulted in the identification of one new and six known compounds. Known compounds were sesquiterpene coumarins: mogoltacin, feselol, badrakemin acetate, ferocaulidin, conferone and conferol acetate. The new compound was a sesquiterpene, named badrakemonin. The structures of these compounds were elucidated by extensive NMR spectroscopic methods including 1D-(1H and 13C) and 2D-NMR (HSQC, HMBC, and ROESY) as well as MS experiments.