The Potential Benefits of Ginger in Cancer Therapy

Shahrzad Momtazan; Shahrzad Ramezani; Alireza Momeni; Abdolkarim Sheikhi

doi:10.5812/tms-142737

The Potential Benefits of Ginger in Cancer Therapy

authors:

Shahrzad Momtazan ¹ , Shahrzad Ramezani ¹ , Alireza Momeni ² , Abdolkarim Sheikhi ^{1
, *}

1 Department of Immunology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran

2 Department of Internal Medicine, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran

Trends in Medical Sciences: Vol.3, issue 2; e142737

published online: November 13, 2023

article type: Letter

received: November 5, 2023

accepted: November 5, 2023

DOI: https://doi.org/10.5812/tms-142737

how to cite: Momtazan S, Ramezani S, Momeni A, Sheikhi A. The Potential Benefits of Ginger in Cancer Therapy. J Adv Immunopharmacol. 2023;3(2):e142737. https://doi.org/10.5812/tms-142737.

Keywords

Ginger Supportive Care Cancer

Footnotes

Authors' Contribution: SM, SR, and AS wrote and revised the manuscript. AS and AM contributed to the writing and revision of the manuscript.
Conflict of Interests: There is no conflict of interest.
Ethical Approval: The study was approved by the Ethics Committee of Dezful University of Medical Sciences (IR.DUMS.REC.1401.049 ).
Funding/Support: This study was supported by the Dezful University of Medical Sciences.

References

1.
Gao D, Zhang Y. Comparative antibacterial activities of crude polysaccharides and flavonoids from Zingiber officinale and their extraction. Asian J Tradit Med. 2010;5(6):235-8.
2.
Han KF, Kumar N, Kim JS. Ginger extract inhibits cell growth and modulates angiogenic factors in ovarian cancer cells. Asian Pacific Journal of Cancer Prevention. 2016;17(9):4245-50.
3.
Prasad S, Tyagi AK. Ginger and Its Constituents: Role in Prevention and Treatment of Gastrointestinal Cancer. Gastroenterol Res Pract. 2015;2015:142979. https://doi.org/10.1155/2015/142979.
4.
Kotowski U, Kadletz L, Schneider S, Foki E, Schmid R, Seemann R, et al. 6-shogaol induces apoptosis and enhances radiosensitivity in head and neck squamous cell carcinoma cell lines. Phytother Res. 2018;32(2):340-7. [PubMed ID: 29168275]. https://doi.org/10.1002/ptr.5982.
5.
Rhode J, Fogoros S, Zick S, Wahl H, Griffith KA, Huang J, et al. Ginger inhibits cell growth and modulates angiogenic factors in ovarian cancer cells. BMC Complement Altern Med. 2007;7:44. [PubMed ID: 18096028]. [PubMed Central ID: PMC2241638]. https://doi.org/10.1186/1472-6882-7-44.
6.
Choi J, Lee J, Kim K, Choi HK, Lee SA, Lee HJ. Effects of Ginger Intake on Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Randomized Clinical Trials. Nutrients. 2022;14(23):4982. [PubMed ID: 36501010]. [PubMed Central ID: PMC9739555]. https://doi.org/10.3390/nu14234982.
7.
Marx W, Ried K, McCarthy AL, Vitetta L, Sali A, McKavanagh D, et al. Ginger-Mechanism of action in chemotherapy-induced nausea and vomiting: A review. Crit Rev Food Sci Nutr. 2017;57(1):141-6. [PubMed ID: 25848702]. https://doi.org/10.1080/10408398.2013.865590.
8.
Ryan JL, Heckler CE, Roscoe JA, Dakhil SR, Kirshner J, Flynn PJ, et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Support Care Cancer. 2012;20(7):1479-89. [PubMed ID: 21818642]. [PubMed Central ID: PMC3361530]. https://doi.org/10.1007/s00520-011-1236-3.
9.
Zadorozhna M, Mangieri D. Mechanisms of Chemopreventive and Therapeutic Proprieties of Ginger Extracts in Cancer. Int J Mol Sci. 2021;22(12):6599. [PubMed ID: 34202966]. [PubMed Central ID: PMC8234951]. https://doi.org/10.3390/ijms22126599.
10.
Sharifi-Rad M, Varoni EM, Salehi B, Sharifi-Rad J, Matthews KR, Ayatollahi SA, et al. Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy. Molecules. 2017;22(12):2145. [PubMed ID: 29207520]. [PubMed Central ID: PMC6149881]. https://doi.org/10.3390/molecules22122145.

comments