Intravenous Drug Sedation for MRI in Children; A Randomized Controlled Trial

Mehrdad Mesbah Kiaei; Arash Jafarieh; Abolghasem Yoosefi

doi:10.22037/jcma.v4i4.28915

Journal of Cellular & Molecular Anesthesia

Editors & Boards Indexing and Listing Sources Journal Information Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement New Publisher Announcement Reviewer and AE Registration Form Contact Us Support

APC

Authors Guide Submit Manuscript

https://doi.org/10.22037/jcma.v4i4.28915

Intravenous Drug Sedation for MRI in Children; A Randomized Controlled Trial

Author(s):

Mehrdad Mesbah Kiaei^1,*,

Arash Jafarieh²,

Abolghasem Yoosefi²

1Assistant Professor of Cardiac Anesthesiology, Department of Anesthesiology and Pain Medicine, Hasheminejad Hospital, Iran University of Medical Sciences, Tehran, Iran

2Assistant Professor, Department of Anesthesiology, Tehran University of Medical Sciences, Amir Alam Hospital Complex, Tehran, Iran

Journal of Cellular & Molecular Anesthesia:Vol. 4, issue 4; e149592

Published online:Mar 24, 2020

Article type:Original Articles

How to Cite:Mehrdad Mesbah KiaeiArash JafariehAbolghasem YoosefiIntravenous Drug Sedation for MRI in Children; A Randomized Controlled Trial.J Cell Mol Anesth.2020;4(4):e149592.https://doi.org/10.22037/jcma.v4i4.28915.

Abstract

Introduction; Performing MRI in children is a matter of concern and needs adequate sedation because patients should be completely motionless to provide a good quality of imaging.? The aim of this study was to compare the effects of Nesdonal and Propofol + Lidocaine to provide sedation in children undergoing brain MRI.Methods; This was a randomized, blinded trial including 250 patients aged 3 months to 13 years who were candidate for elective brain MRI. Participants were divided into two groups. Group 1 received Nesdonal and group 2 received Propofol + Lidocaine. Demographic characteristics were recorded. Unconsciousness time, scan time and discharge time were compared between the two groups. Data was analyzed using SPSS version 16 by Chi-square, ANOVA, Man-Whitney and T-test (p value < 0.05).Results; Totally 250 patients were assigned randomly to two groups of Propofol + Lidocaine and Nesdonal, each including 125 patients. There was no meaningful difference regarding demographic factors of age, gender or ASA class between the two groups. There was no meaningful statistically difference regarding unconsciousness time (P value=0.655), scan time (P value=0.324) and discharge time (P value=0.436) between the Propofol + Lidocaine and Nesdonal group. Some minor adverse effects occurred in the Propofol + Lidocaine group. No major complication occurred.Discussion; Nesdonal was superior to Propofol + Lidocaine regarding lower adverse effects, lower costs, no need for an infusion pump and not lowering seizure threshold.it can be considered safe for sedation in children undergoing brain MRI, especially those with a history of seizure.

Keywords

References

1.
References are in the PDF file of the article.

comments

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

CrossRef 0

Metrics

Get Permission (article level)

Purchasing Reprints

Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.

Search Relations

Author(s):

Mehrdad Mesbah Kiaei:[PubMed][Scholar]
Arash Jafarieh:[PubMed][Scholar]
Abolghasem Yoosefi:[PubMed][Scholar]