Prevalence of Rare and Common Bleeding Disorders in Kurdistan Province of Iran

Akbar Dorgalaleh; Jamal Rashid Panah; Bijan Varmaghani; Peyman Beigi; Abbas Ahmadi

doi:10.22037/jcma.v4i4.29074

Journal of Cellular & Molecular Anesthesia

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https://doi.org/10.22037/jcma.v4i4.29074

Prevalence of Rare and Common Bleeding Disorders in Kurdistan Province of Iran

Author(s):

Akbar Dorgalaleh^1,*,

Jamal Rashid Panah²,

Bijan Varmaghani³,

Peyman Beigi⁴,

Abbas Ahmadi⁵

1Department of Hematology abd Blood Transfusion, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran

2Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

3Tehran Hear Center, Tehran University of Medical Sciences, Tehran, Iran

4Department of Hematology and Blood Transfusion, Tarbiat Modares University, Tehran, Iran

5Cellular and Molecular Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran

Journal of Cellular & Molecular Anesthesia:Vol. 4, issue 4; e149593

Published online:Mar 24, 2020

Article type:Original Articles

How to Cite:Akbar DorgalalehJamal Rashid PanahBijan VarmaghaniPeyman BeigiAbbas AhmadiPrevalence of Rare and Common Bleeding Disorders in Kurdistan Province of Iran.J Cell Mol Anesth.2020;4(4):e149593.https://doi.org/10.22037/jcma.v4i4.29074.

Abstract

Background: Congenital bleeding disorders (CBD) are a group of coagulopathies with different clinical and laboratory features. The prevalence of these disorders in different parts of the world is variable. Iran as a country with a high rate of parental consanguinity has a high rate of CBDs. This study was to report the prevalence of these disorders in Kurdistan province, west of Iran.Methods and materials: This descriptive study was conducted on patients suspected of a congenital bleeding disorder referred to hemophilia center of this province for evaluation of underlying bleeding diathesis. Diagnosis and classification of disorders were made by routine and specific laboratory tests.Results: Out of 107 patients, 65.4% affected by common bleeding disorders (hemophilia A and B), 23.4% affected by rare bleeding disorders (RBDs) and 11.2% had inherited platelet disorders. Factor VII deficiency (64%) was the most common RBDs and 9 patients had von Willebrand disease. Out of three patients with inherited platelet disorders, two had Glanzmann thrombasthenia.Conclusion: CBD pattern though has similar patterns with total pattern of the country, some of the inherited platelet disorders are more common in Kurdish province. Determination of prevalence and distribution of these disorders can improve health system planning and resource allocation.Keywords: Congenital bleeding disorders, Rare bleeding disorders, Common bleeding disorders, inherited platelet disorders

Keywords

Congenital bleeding disorders

Rare bleeding disorders

Common bleeding disorders

Inherited platelet disorders

References

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References are in the PDF file of the article.

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Author(s):

Akbar Dorgalaleh:[PubMed][Scholar]
Jamal Rashid Panah:[PubMed][Scholar]
Bijan Varmaghani:[PubMed][Scholar]
Peyman Beigi:[PubMed][Scholar]
Abbas Ahmadi:[PubMed][Scholar]