Neurologic Manifestations of COVID-19: A Case Series of Iranian Patients

authors:

avatar Farhad Malek , * , avatar Nooshin Masoodian 1 , avatar Afshin Samaei , avatar Ali Gohari 1 , avatar Sara Reshadat 1 , avatar Hoda Aryan 2 , avatar Mahboobeh Darban 1 , avatar Bahador Bagheri ORCID 3

Semnan University of Medical Sciences, Semnan, Iran
Department of Internal Medicine, Kowsar Hospital, Semnan University of Medical Sciences, Semnan, Iran
Department of Pharmacology, Semnan University of Medical Sciences, Semnan, Iran

how to cite: Malek F, Masoodian N, Samaei A, Gohari A, Reshadat S, et al. Neurologic Manifestations of COVID-19: A Case Series of Iranian Patients. J Cell Mol Anesth. 2020;5(4):e149635. https://doi.org/10.22037/jcma.v5i4.31261.

Abstract

Introduction:?Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is declared a pandemic disease by the World Health Organization. Although the respiratory and cardiovascular systems are preferentially affected by SARS-CoV-2, many patients have been presented with neurologic symptoms. In this report, we describe COVID-19 patients with neurological manifestations. Case Presentation:?We present 14 patients referred to Semnan Kowsar Hospital. The mean age at presentation was 54.25 ? 20.01 years with a range of 24-84 yr. At admission, they had mild symptoms of respiratory involvement. In contrast, they had a wide range of neurological conditions like impaired consciousness, seizure, stroke, ataxia, and muscle numbness. After hospitalization, they developed overt respiratory symptoms. They were positive for COVID-19 confirmed by real-time PCR. All cases received standard care of COVID-19. Conclusions: During the?SARS-CoV-2 pandemic disease, patients with neurological manifestations might be affected by coronavirus. Such patients should be thoroughly evaluated and followed-up.