Role of IL-4 in Cytokine Storm Syndrome due to COVID-19 Infection

authors:

avatar Rahim Soleimani Gelodar 1 , * , avatar Sepideh Nasimzadeh 2 , avatar Amin Dehghan Banadkouki 3 , avatar milad zandi 1

Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Virology Department, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

how to cite: Soleimani Gelodar R, Nasimzadeh S, Dehghan Banadkouki A, zandi M. Role of IL-4 in Cytokine Storm Syndrome due to COVID-19 Infection. J Cell Mol Anesth. 2020;5(4):e149656. https://doi.org/10.22037/jcma.v5i4.32344.

Abstract

SARS-CoV-2 that causes Coronavirus disease 2019 (COVID-19) is a spreading global threat. COVID-19 declared as a pandemic by the WHO. COVID-19 is transmitted by direct contact or droplets and can infect the respiratory tract which resulting in acute respiratory distress syndrome (ARDS) and pneumonia in most of cases. IL-4 as a Th2 cytokines has different roles in coronaviruses infections. In this article we focused on function of IL-4 in COVID-19.