Autophagy Role as a Double-Edged Sword in Anesthesiology and Critical Care

authors:

avatar milad zandi 1 , * , avatar Parnian Ghadimi 2 , avatar Maryam Fazeli 1 , avatar Farid Azizi Jalilian 3 , avatar Maryam Fazeli 4 , avatar Emad Behboudi 5 , avatar Dr Behzad Pourhossain 6

Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Department of Medical Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
Department of Virology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Journal of Cellular & Molecular Anesthesia: Vol.6, issue 1; e149657
article type: Review
DOI: https://doi.org/10.22037/jcma.v6i1.32381

how to cite: zandi M, Ghadimi P , Fazeli M, Azizi Jalilian F, Fazeli M, et al. Autophagy Role as a Double-Edged Sword in Anesthesiology and Critical Care. J Cell Mol Anesth. 2021;6(1):e149657. https://doi.org/10.22037/jcma.v6i1.32381.

Abstract

Autophagy is a mechanism, which host cells can utilize it to defend against infections. Trapped cargo such as viral cargo and delivered to a lysosome for degradation. Primary immune response against some viruses can start by autophagy mechanism. In this study, we reviewed role of autophagy in viral infections.