Can COVID-19 Be a risk factor for tuberculosis? COVID-19 and tuberculosis

authors:

avatar Benyamin Parseh 1 , * , avatar ehsan allah kalteh ORCID 2 , avatar Mahnaz Sheikhi 3 , avatar mousa ghelichi ghojogh ORCID 4

PhD Applied Cell sciences, Faculty of Advanced Medical Technologies, Golestan University of Medical Sciences, Gorgan, Iran
MSc of Epidemiology, Infectious Disease Research Center, Golestan University of Medical Sciences, Gorgan, Iran
General Practitioner, Golestan University of Medical Sciences, Gorgan, Iran
PhD Student in Epidemiology, Student Research Commitee, Shiraz University of Medical Sciences, Shiraz, Iran.

how to cite: Parseh B , kalteh E A, Sheikhi M , ghelichi ghojogh M. Can COVID-19 Be a risk factor for tuberculosis? COVID-19 and tuberculosis. J Cell Mol Anesth. 2021;6(1):e149662. https://doi.org/10.22037/jcma.v6i1.32694.

Abstract

?Most COVID-19 severe cases are presented with uncontrolled elevated level of proinflammatory cytokines such as IL-6, IL-1?, IL-2?? IL-8, IL-17, G- CSF, GM- CSF, IP10, MCP1, CCL3, and TNF which is called cytokine storm. Previous studies showed that proinflammatory cytokine overexpression such as TNF and IL-6 exacerbates TB. In COVID-19 patients, we are facing immune system imbalance due to cytokine storm. Thus, COVID-19 may be a predisposing factor to turn latent TB to active TB.