Assessment of the Effect of Granisetron on the Gastric Cross-Sectional Area By Ultrasound on Patients Undergoing Elective Cesarean Section: A Randomized Double-Blind Study

How to Cite:Saeid ElsawyMohamed Elkhateebrasha hamedZein ZareeAssessment of the Effect of Granisetron on the Gastric Cross-Sectional Area By Ultrasound on Patients Undergoing Elective Cesarean Section: A Randomized Double-Blind Study.J Cell Mol Anesth.8(2):e149677.https://doi.org/10.22037/jcma.v8i2.38778.

Abstract

Background: Gastric ultrasound is considered a valuable tool for the assessment of gastric volume preoperatively. Materials and Methods: The goal of this study was to assess the effect of granisetron on the gastric cross-sectional area by ultrasound estimation of its cross-sectional area for elective Cesarean Section. Sixty patients were assigned randomly into one of 2 groups; Granisetron group (n=30): received 1 mg granisetron diluted in 10 mL normal saline 0.9%. Control (n=30): received 10 mL of normal saline 0.9%. Cross-sectional area and volume of stomach contents were measured using ultrasound immediately before administration of the study drug and one hour later. Results: No statistical difference was detected in post-treatment antral CSA nor gastric residual volume between the two groups (4.8?1.4 vs 4.6?2.1, P: 0.8) and (50?19 vs 57?27, P: 0.3) for antral CSA and gastric volume comparison between both groups. However, a significant statistical difference was found in antral CSA pre and post-granisetron administration (4.8?1.4 vs 4 ?1.2; P<0.001). The Granesitron group had a statistically significantly lower rate of nausea and vomiting than the control group. Conclusion: Based on ultrasonographic measurement granesitron could effectively reduce the gastric cross-sectional area when administered preoperatively to parturients undergoing elective CS.

Keywords

gastric POCUS

gastric cross sectional area

granesitron

pregnancy

References

1.
References are in the PDF file of the article.

comments

Crossmark

Checking

Share on

Comments

Number of Comments:0

Cited by

CrossRef 0

Metrics

Get Permission (article level)

Purchasing Reprints

Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here ( https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.

Search Relations

Author(s):

Saeid Elsawy:[PubMed][Scholar]
Mohamed Elkhateeb:[PubMed][Scholar]
rasha hamed:[PubMed][Scholar]
Zein Zaree:[PubMed][Scholar]