Spike Protein Mutations and the Effects on SARS-CoV-2 Pathogenesis

authors:

avatar milad zandi , * , avatar Saber Soltani ORCID , avatar Samira sanami , avatar Azadeh Rasooli

Journal of Cellular & Molecular Anesthesia: Vol.6, issue 2; e150287
published online: April 16, 2021
article type: Review
DOI: https://doi.org/10.22037/jcma.v6i2.33800

how to cite: zandi M, Soltani S, sanami S , Rasooli A. Spike Protein Mutations and the Effects on SARS-CoV-2 Pathogenesis. J Cell Mol Anesth. 2021;6(2):e150287. https://doi.org/10.22037/jcma.v6i2.33800.

Abstract

The severe acute respiratory syndrome coronavirus 2 spike (S) glycoprotein facilitates receptor binding to initiate cell entry that is the critical initial step in the infection cycle. Due to S glycoprotein's pivotal role, in this review, we pointed to show potential functional and structural consequences of S glycoprotein and its variants, which has been related with increased viral load in humans with SARS-CoV-2 infection.

References

  • 1.

    References are in the PDF file of the article.