The First Case of Type A Botulism Associated with Eating Barbecued Caviar Fish Zohreh

Zohreh Amin zadeh; Parviz Vahdani; Shahram Mortazavi

Journal of Comprehensive Pediatrics

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The First Case of Type A Botulism Associated with Eating Barbecued Caviar Fish Zohreh

Author(s):

Zohreh Amin zadeh^1,*,

Parviz Vahdani²,

Shahram Mortazavi²,

1Department of Infectious Diseases, Infectious Disease and Tropical Medicine Research Center, Shaheed Beheshti University of Medical Sciences and Health Services, zohrehaminzadeh@yahoo.com, IRAN

2Department of Infectious Diseases, Infectious Disease and Tropical Medicine Research Center, Shaheed Beheshti University of Medical Sciences and Health Services, IRAN

Journal of Comprehensive Pediatrics:Vol. 1, issue 1; 67-69

Article type:Case Report

Received:Jan 01, 2007

Accepted:Jan 01, 2007

How to Cite:Zohreh Amin zadehParviz VahdaniShahram Mortazavi The First Case of Type A Botulism Associated with Eating Barbecued Caviar Fish Zohreh.J Compr Ped.1(1):67-69.

Abstract

Botulism is a paralytic illness caused by the neurotoxin of clostridium botulinium. Food born botulism may develop after eating foods contaminated with botulinium toxin. Botulinium neurotoxin predominantly affects the peripheral neuromuscular junction and autonomic synapse, and its effects are primarily manifested as weakness.
A 12-year-old boy presented with severe weakness, diplopia and dropping eyelids 6 hours following ingestion of barbecued caviar fish. Clinical presentations were constipation, dry mouth, diplopia, blurred vision, ptosis, dilated and reactive pupils, weakness and lethargy. Based on the clinical findings, the patient received three antitoxin A, B, E monovalent; and stool, gastric fluid as well as serum samples were sent for toxicological evaluation with standard mouse bioassay. Type A toxin was detected in stool sample of the patient. Ten days later, the patient was discharged in a good condition. This study confirmed that prompt administration of antitoxin can prevent progression of disease based on clinical judgment and may also be life saving.

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