Kawasaki Disease

Ahmad Siadati; Farah Sabouni; Parisa Saleh Anaraki

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Kawasaki Disease

Author(s):

Ahmad Siadati^1,*,

Farah Sabouni²,

Parisa Saleh Anaraki²,

1Department of Pediatrics, Tehran University of Medical Sciences and Health Services, [email protected], IRAN

2Department of Pediatrics, Tehran University of Medical Sciences and Health Services, IRAN

Journal of Comprehensive Pediatrics:Vol. 1, issue 1; 9-23

Article type:Review Article

Received:Jan 01, 2007

Accepted:Jan 01, 2007

How to Cite:Ahmad Siadati, Farah Sabouni, Parisa Saleh Anaraki, , Kawasaki Disease.J Compr Ped.1(1):9-23.

Abstract

Kawasaki disease is an acute vasculitis of childhood that predominantly affects the coronary arteries. The etiology of Kawasaki disease remains unknown, although an infectious agent is strongly suspected based on clinical and epidemiologic features. A genetic predisposition is also likely, based on varying incidences among ethnic groups, with higher rates in Asians. Symptoms include fever, conjunctival injection, erythema of the lips and oral mucosa, rash, and cervical lymphadenopathy. Some children with Kawasaki disease develop coronary artery aneurysms or ectasia, ischemic heart disease, or sudden death. Kawasaki disease is the leading cause of acquired heart disease among children in developed countries. This article provides a summary of the history, etiology, clinical diagnosis, treatment guidelines and lifelong follow up of KD.

Keywords

Coronary artery aneurysm

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