1. Background
2. Objectives
3. Methods
3.1. Inclusion Criteria
3.2. Exclusion Criteria
3.3. Ethical Issues
4. Results
| Variables | Pre-test | Post-test |
|---|---|---|
| TDCS intervention group | ||
| Self-management of time | 64.13 ± 10.80 | 79.13 ± 12.27 |
| Self-organization and problem-solving | 71 ± 14.95 | 76.2 ± 12.7 |
| Self-discipline/inhibition | 57.66 ± 5.47 | 63.66 ± 10.23 |
| Self-motivation | 32.13 ± 5.02 | 40.2 ± 5.49 |
| Emotional self-regulation | 29.6 ± 5.32 | 45.93 ± 8.69 |
| Total score | 254.53 ± 25.85 | 305.13 ± 29.77 |
| Sham/placebo group | ||
| Self-management of time | 68.46 | |
| Self-organization and problem-solving | 78.06 ± 10.06 | 70.06 ± 14.16 |
| Self-discipline/inhibition | 56.93 ± 5.92 | 55.46 ± 8.33 |
| Self-motivation | 29.46 ± 5.71 | 30.2 ± 3.29 |
| Emotional self-regulation | 31 ± 3.92 | 30.53 ± 4.37 |
| Total score | 263.93 ± 24.61 | 248.8 ± 27.35 |
| Cognitive rehabilitation intervention group | ||
| Self-management of time | 68.8 ± 10.33 | 70.66 ± 15.76 |
| Self-organization and problem-solving | 64.34 ± 10.33 | 70.66 ± 15.76 |
| Self-discipline/inhibition | 42.06 ± 6.41 | 62.26 ± 7.58 |
| Self-motivation | 25.4 ± 4.2 | 30.73 ± 5.27 |
| Emotional self-regulation | 31.20 ± 5.22 | 35.93 ± 5.54 |
| Total score | 221.8 ± 12.48 | 278.33 ± 19.5 |
| Control group | ||
| Self-management of time | 68.13 ± 10.14 | 68.06 ± 12.16 |
| Self-organization and problem-solving | 74.33 ± 15.12 | 72.86 ± 16.3 |
| Self-discipline/inhibition | 51.13 ± 5.62 | 52.26 ± 6.47 |
| Self-motivation | 27.4 ± 3.99 | 25.93 ± 3.3 |
| Emotional self-regulation | 35.2 ± 6.41 | 32.06 ± 7.44 |
| Total score | 256.2 ± 26.4 | 251.46 ± 25.36 |
a Values are expressed as mean ± SD.
| Tests | Values | F | Hypothesis df | Error df | P-Value a | Partial Eta Squares |
|---|---|---|---|---|---|---|
| Pilla’s trace | 0.783 | 13.7 | 6 | 23 | **0.0001 | 0.783 |
| Willk’s lambda | 0.217 | 13.7 | 6 | 23 | **0.0001 | 0.783 |
| Hotelling’s trace | 3.6 | 13.7 | 6 | 23 | **0.0001 | 0.783 |
| Roy’s largest root | 3.6 | 13.7 | 6 | 23 | **0.0001 | 0.783 |
a ** P < 0.01 & * P < 0.05. Significant level from MANCOVA with pre-test control compatible with intervention effectiveness.
| Sources | Sum of Squares | Degrees of Freedom | Mean of Squares | F | Significance Level | Partial Eta Squares |
|---|---|---|---|---|---|---|
| Self-management of time | ||||||
| Pre test | 87.47 | 1 | 87.47 | 0.432 | 0.571 | 0.016 |
| Group | 50.7 | 1 | 50.7 | 0.256 | 0.617 | 0.009 |
| Error | 5554.26 | 28 | 198.36 | |||
| Self-organization and problem-solving | ||||||
| Pre test | 2.7 | 1 | 2.7 | 0.015 | 0.905 | 0.0001 |
| Group | 208.03 | 1 | 208.03 | 1.17 | 0.288 | 0.04 |
| Error | 4975.46 | 28 | 177.69 | |||
| Self-discipline/inhibition | ||||||
| Pre test | 79.69 | 1 | 79.69 | 1.66 | 0.211 | 0.057 |
| Group | 750 | 1 | 750 | 15.08 | **0.001 | 0.35 |
| Error | 1391.86 | 28 | 49.71 | 0.845 | 0.366 | |
| Self-motivation | ||||||
| Pre test | 16.43 | 1 | 16.43 | 8.92 | **0.006 | 0.03 |
| Group | 172.8 | 1 | 172.8 | 0.26 | ||
| Error | 541.86 | 28 | 19.35 | 2.65 | 0.115 | |
| Emotional self-regulation | ||||||
| Pre test | 118.07 | 1 | 118.07 | 2.59 | 0.118 | 0.006 |
| Group | 112.13 | 1 | 112.13 | 0.085 | ||
| Error | 1207.86 | 28 | 43.13 | |||
| Total score | ||||||
| Pre test | 47.13 | 1 | 47.13 | 0.089 | 0.76 | 0.003 |
| Group | 5413.63 | 1 | 5413.63 | 10.75 | **0.003 | 0.27 |
| Error | 14333.06 | 28 | 511.89 | |||
| Total | ||||||
| Self-management of time | 14333.03 | 30 | ||||
| Self-organization and problem-solving | 19957 | 30 | ||||
| Self-discipline/inhibition | 176191 | 30 | ||||
| Self-motivation | 100526 | 30 | ||||
| Emotional self-regulation | 24798 | 30 | ||||
| Total score | 2124907 |
a ** P < 0.01 & *P < 0.05. Significant level from MANCOVA with pre-test control compatible with intervention effectiveness.
| Tests | Values | F | Hypothesis df | Error df | P-Value a | Partial Eta Squares |
|---|---|---|---|---|---|---|
| Pilla’s trace | 0.595 | 5.62 | 6 | 23 | **0.0001 | 0.595 |
| Willk’s lambda | 0.405 | 5.62 | 6 | 23 | **0.0001 | 0.595 |
| Hotelling’s trace | 1.467 | 5.62 | 6 | 23 | **0.0001 | 0.595 |
| Roy’s largest root | 1.467 | 5.62 | 6 | 23 | **0.0001 | 0.595 |
a ** P < 0.01 & *P < 0.05. Significant level from MANCOVA with pre-test control compatible with intervention effectiveness.
| Sources | Sum of Squares | Degrees of Freedom | Mean of Squares | F | Significance Level | Partial Eta Squares |
|---|---|---|---|---|---|---|
| Self-management of time | ||||||
| Pre test | 87.47 | 1 | 87.47 | 0.432 | 0.571 | 0.016 |
| Group | 50.7 | 1 | 50.7 | 0.256 | 0.617 | 0.009 |
| Error | 5554.46 | 28 | 198.36 | |||
| Self-organization and problem-solving | ||||||
| Pre test | 2.7 | 1 | 2.7 | 0.015 | 0.905 | 0.0001 |
| Group | 208.03 | 1 | 208.03 | 1.17 | 0.288 | 0.04 |
| Error | 4975.46 | 28 | 177.69 | |||
| Self-discipline/inhibition | ||||||
| Pre test | 79.69 | 1 | 79.69 | 1.64 | 0.211 | 0.057 |
| Group | 750 | 1 | 750 | 15.08 | **0.001 | 0.35 |
| Error | 1391.86 | 28 | 49.71 | |||
| Self-motivation | ||||||
| Pre test | 16.43 | 1 | 16.43 | 0.845 | 0.366 | 0.03 |
| Group | 172.8 | 1 | 172.8 | 8.92 | **0.006 | 0.26 |
| Error | 541.86 | 28 | 19.35 | |||
| Emotional self-regulation | ||||||
| Pre test | 118.07 | 1 | 118.07 | 2.65 | 0.115 | 0.006 |
| Group | 112.13 | 1 | 112.13 | 2.59 | 0.118 | 0.085 |
| Error | 1207.86 | 28 | 43.13 | |||
| Total score | ||||||
| Pre test | 47.13 | 1 | 47.13 | 0.089 | 0.76 | 0.003 |
| Group | 5413.63 | 1 | 5413.63 | 10.75 | **0.003 | 0.27 |
| Error | 14333.06 | 28 | 511.89 | |||
| Total score of execute functions | ||||||
| Self-management of time | 14333.03 | 30 | ||||
| Self-organization and problem-solving | 1419957 | 30 | ||||
| Self-discipline/inhibition | 176191 | 30 | ||||
| Self-motivation | 100526 | 30 | ||||
| Emotional self-regulation | 24798 | 30 | ||||
| Total score | 2124907 |
a ** P < 0.01 & *P < 0.05. Significant level from MANCOVA with pre-test control compatible with intervention effectiveness.
| Dependent Variable | Groups (i) | Groups (j) | Mean Difference | Standard Error | Significance |
|---|---|---|---|---|---|
| Self-management of time | TDCS | Cognitive rehabilitation group | 11.8 | 4.47 | *0.019 |
| TDCS | Sham/placebo group | 15.34 | 5.28 | **0.005 | |
| Cognitive Rehabilitation | Control group | 3.12 | 6.56 | 0.636 | |
| Self-organization and problem-solving total score of executive functions | TDCS | Cognitive rehabilitation group | 3.55 | 7.19 | 0.624 |
| TDCS | Sham/placebo group | 7.16 | 5.47 | 0,195 | |
| Cognitive Rehabilitation | Control group | 2.76 | 6.77 | 0.689 | |
| Self-discipline/inhibition | TDCS | Cognitive rehabilitation group | 1.38 | 4.46 | 0.758 |
| TDCS | Sham/placebo group | 7.48 | 3.38 | *0.031 | |
| Cognitive Rehabilitation | Control group | 8.76 | 4.19 | *0.042 | |
| Self-motivation | TDCS | Cognitive rehabilitation group | 10.39 | 2.34 | **0.0001 |
| TDCS | Sham/placebo group | 10.17 | 1.77 | **0.0001 | |
| Cognitive rehabilitation | Control group | 4.51 | 2.2 | *0.046 | |
| Emotional self-regulation | TDCS | Cognitive rehabilitation group | 6.29 | 3.58 | 0.085 |
| TDCS | Sham/placebo group | 15.8 | 2.71 | **0.0001 | |
| Cognitive rehabilitation | Control group | 7.03 | 3.37 | *0.042 | |
| Total score of executive functions | TDCS | Cognitive rehabilitation group | 28.21 | 13.69 | *0.045 |
| TDCS | Sham/placebo group | 58.21 | 10.37 | **0.0001 | |
| Cognitive rehabilitation | Control group | 26.8 | 12.89 | *0.043 |
a ** P < 0.01 & *P < 0.05. Significant level from MANCOVA with pre-test control compatible with intervention effectiveness.