Survey the hepatitis B serologic markers in patients referred to the clinic of Kermanshah University of Medical Sciences

authors:

avatar Alisha Akya 1 , avatar Mehrdad Khodadoost 2 , * , avatar Farzaneh Mohebi 3 , avatar Milad Dehghani 4 , avatar Maryam Amighi 5

Nosocomial Infection Research Center, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Andorra
Abadan Branch, Islamic Azad University, Abadan, Iran 3. Clinic of Kermanshah University of Medical Sciences, Kermanshah, Iran
Clinic of Kermanshah University of Medical Sciences, Kermanshah, Iran
Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran
Department of Midwifery, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran

how to cite: Akya A , Khodadoost M , Mohebi F, Dehghani M , Amighi M . Survey the hepatitis B serologic markers in patients referred to the clinic of Kermanshah University of Medical Sciences. J Clin Res Paramed Sci. 2016;5(1):e81441. 

Abstract

Introduction: Despite an effective vaccine against hepatitis B (HBV), infection with this virus is still one of the most common community-acquired infections. HBV infection is usually diagnosed using serological and virological parameters. We aimed to investigate the prevalence of hepatitis B serologic markers in patients referred to the clinic of Kermanshah University of Medical Sciences during 2011-2012.
Methods: Blood was obtained from 3561patients and centrifuged. Blood serum was separated and kept at -20 °C until testing. The antigen and antibodies of hepatitis B virus were examined using ELISA method.
Results: A total of 3561 persons were tested for HBsAg and the prevalence of hepatitis B was 3.08% for this population. The highest rate of HBsAg (60.9%) was for 40-21 year old and the lowest (0%) was in children under 10 years. In this study, 167 patients (4.5%) were tested for HbsAb. Of them 105 (63%) cases were positive which consisted of 57 (54.28%) women and 48 (45.71%) men. 
Conclusion: The prevalence of HBV infection in the elderly and middle-aged  people was more than youngers. It seems thah the prevalence of HBV infection after the national vaccination program for hepatitis B in children and adolescents has decreased in the community.

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