Seroepidemiology of Toxoplasmosis in Pregnant Women Referred to Reference laboratory in Kermanshah, 2014-2015

authors:

avatar Bahare Zalei 1 , avatar Daryoush Pourmand 2 , * , avatar Soraya bilvaye 3 , avatar Haleh Jalilzadeh hamidi 4

Imam Ali hospital, Kermanshah university of medical sciences, Kermanshah, Iran
Department of medical laboratory sciences, school of paramedicine, Kermanshah university of medical sciences, kermanshah, Iran
Department of immunology , school of medicine, , Kermanshah university of medical sciences, Kermanshah, Iran
Taleghani hospital, Kermanshah university of medical sciences, Kermanshah, Iran
Journal of Clinical Research in Paramedical Sciences: Vol.5, issue 2; e81462
published online: June 12, 2016
article type: Research Article
received: November 12, 2015
accepted: April 20, 2016

how to cite: Zalei B , Pourmand D , bilvaye S, Jalilzadeh hamidi H . Seroepidemiology of Toxoplasmosis in Pregnant Women Referred to Reference laboratory in Kermanshah, 2014-2015. J Clin Res Paramed Sci. 2016;5(2):e81462. 

Abstract

Introduction:Toxoplasmosis is a common parasitic infection in most of areas in the world which is caused by protozoan parasite called Toxoplasma gondii. Toxoplasma gondii can be vertically transmitted to the fetus during pregnancy and may cause awid range of clinical manifistations like prenatal mortality, abortion or congenital defects. The aim of this study was to determination of seroepidemiology of Toxoplasma infection in pregnant women referred to Reference Laboratory in Kermanshah during 2014 and study of realationship between toxoplasmosis rate and risk factors like age ,contact by animals  nutriation and other factors.
Methods: In this cross-sectional descriptive study,Serum samples of 386 pregnant women were investigated for existence of IgG antibodies against Toxoplasma by Enzyme Linked Immunosorbent Assay (ELISA) method. A questionnaire about demographic characteristic and risk factors of cases was filled in. The data analyzed using SPSS software version 16.
Results: In this study, in 386 pregnant women, 133 cases (34.5%) had positive serology tests. The mean age cases, was 29 years old There are significant realationship between infection rate and domestic animal contact (p<0.001) and significant realationship between infection rate and age was seen too (p-value=0.001). 
Conclusion::Results of this study showed, the seroprevalence of Toxoplasmosis in pregnant women in Kermanshah is 34.5%. ,it is essential to do Serological screening tests in first trimester of pregnancy and it is possible to prevent of congenital Toxoplasmosis whit health educational programs.

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