Abstract
Introduction: Most blood group alloantibodies are generated by mismatched transfusion as
the result of foreign erythrocyte antigen exposure to the immune system. This study was done
to determine the frequency of blood group alloantibodies in patients who admitted in Ghaem
hospital of Mashhad-Iran.
Method: This cross sectional study was done on 525 patientsin Ghaem Hospital of Mashhad
University of Medical Sciences. The ABO and Rh Blood groups were typed by two methods
of cell type and back type. Red blood cell alloantibodies were detected in patients' serum by
screen antibody kit. All data recorded in computer and analyzed by SPSS version13.
Result: 296 of 525 patients were male and 229 of them were female. Red cell antibodies
were detected in 48 patients consisting one autoantibody and 47 alloantibodies. Warm
allantibodies found in 11 patients and cold alloantibodies detected in 36 patients.
Conclusion: Higher frequency of all immunization was observed in female in compare to
male. This study demonstrates the relationship between the type of blood group and existence
of cold alloantibody. The higher frequency of cold alloantibodies was in people with B blood
group type.
the result of foreign erythrocyte antigen exposure to the immune system. This study was done
to determine the frequency of blood group alloantibodies in patients who admitted in Ghaem
hospital of Mashhad-Iran.
Method: This cross sectional study was done on 525 patientsin Ghaem Hospital of Mashhad
University of Medical Sciences. The ABO and Rh Blood groups were typed by two methods
of cell type and back type. Red blood cell alloantibodies were detected in patients' serum by
screen antibody kit. All data recorded in computer and analyzed by SPSS version13.
Result: 296 of 525 patients were male and 229 of them were female. Red cell antibodies
were detected in 48 patients consisting one autoantibody and 47 alloantibodies. Warm
allantibodies found in 11 patients and cold alloantibodies detected in 36 patients.
Conclusion: Higher frequency of all immunization was observed in female in compare to
male. This study demonstrates the relationship between the type of blood group and existence
of cold alloantibody. The higher frequency of cold alloantibodies was in people with B blood
group type.
Keywords
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Copyright
© 2013, Journal of Clinical Research in Paramedical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.