Abstract
Abstract
Background: The recurrence rate of pterygia after excision is high.
Objective: To determine the effect of rubbing mitomycin-C combined with operation on reduction of the recurrence rate of pterygia, compared to surgical treatment.
Methods: 32 patients with pterygium who were operated by bare-scleral technique in Avi-Cina hospital of Qazvin during 1996 to 1998 were understudy in which 15 cases were treated by surgery (control group) and 17 cases by rubbing mitomycin-C (0.2 mg/ml) combined with surgery intraopratively and postopratively once a day for three consequative days. The average length of follow-up was 18 ± 3 months.
Findings: The recurrences rate of pterygium operated by mitomycin-C was 5.9% which appeared four months after the operation and 40% in control group (P<0.05).
Conclusion: Rubbing mitomycin-C with a concentration of 0.2 mg/ml once a day for three consequitive days can decrease the recurrence rate of pterygium.
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Copyright
© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.