Airborne fungi in Isfahan and evaluation of allergenic responses of their extracts in animal model

Mostafa Chadeganipour; Shahla Shadzi; Shahi Nilipour; Gholamreza Ahmadi

Jundishapur Journal of Microbiology

Ahvaz Jundishapur University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Editors & Boards Journal Information Indexing and Listing Sources Journal Metrics Reviewer and AE Registration Form Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support

APC

Authors Guide Submit Manuscript

Airborne fungi in Isfahan and evaluation of allergenic responses of their extracts in animal model

Author(s):

Mostafa Chadeganipour^1,*,

Shahla Shadzi²,

Shahi Nilipour²,

Gholamreza Ahmadi²

1Department of Medical Mycology and Parasitology, School of Medicine, Isfahan University of Medical Sciences, [email protected], Iran

2Department of Medical Mycology and Parasitology, School of Medicine, Isfahan University of Medical Sciences, Iran

Jundishapur Journal of Microbiology:Vol. 3, issue 4; 155-160

Article type:Research Article

Received:Apr 01, 2010

Accepted:Jun 01, 2010

How to Cite:Mostafa ChadeganipourShahla ShadziShahi NilipourGholamreza AhmadiAirborne fungi in Isfahan and evaluation of allergenic responses of their extracts in animal model.Jundishapur J Microbiol.3(4):155-160.

Abstract

Introduction and objective: Detection of the common allergen airborne fungi in any region is critical for prevention and treatment of allergic fungal diseases. Therefore, this study was conducted to identify the most common airborne fungal species of Isfahan, investigate their allergic reactions in animal and obtain local fungal strains for use as antigens in allergy tests to be used.

Materials and methods: An open plate method was used to scan airborne fungal contents over 12 months in Isfahan. On the same days every week, triplicate samples were collected at three different locations in the morning, at noon and in the evening. The fungal culture media were incubated at 25ºC until growth appeared and then the airborne fungi were identified by routine mycological laboratory methods. The extracts of the most common airborne fungi isolated, were examined with skin prick test for allergic reactions in laboratory animals.

Results: During this study, the most abundant airborne fungi identified in Isfahan were species of yeasts, yeast like (Candida spp., Geotrichum spp., and Trichosporon spp.), and mold (Cladosporium spp., Penicillium spp., Aspergillus spp., and Alternaria). Positive skin reactions were observed with Cladosporium spp.(40%), and Aspergillus spp. (21%), Alternaria spp. (17%), Penicillum spp. (15%) and Geotrichum spp. (7%).

Conclusion: It is concluded that fungi have a significant role in infecting immunocompromised hosts, information obtained in the present study contribute toward a better understanding of the pattern of occurrence of airborne fungi, and may assist allergists, clinicians and epidemiologists to treat the diseases.

Keywords

Full Text

Full text is available in PDF

comments